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Transition Metal Complexes of an Adamantane-Containing Schiff Base Ligand: Synthesis, Structural Characterization and Bioactivity

Author

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  • Jalpa G. Gadara
  • Manhar V. Parsania

Abstract

Novel adamantane-based Schiff base ligands, (E)-N′-(2-hydroxybenzylidene)adamantane-1-carbohydrazides, and their Cu(II), Co(II), Ni(II), Fe(II), Mn(II), Zn(II), Cr(III), and Ce(III) complexes were synthesized and characterized by FT-IR, UV–Vis, NMR, mass spectrometry, elemental analysis, and magnetic measurements. Spectral data confirmed bidentate coordination through phenolic oxygen and azomethine nitrogen atoms. The ligand and its metal complexes were evaluated for antibacterial and antifungal activities, showing enhanced biological activity upon metal coordination compared to the free ligand. The results demonstrate the potential of adamantane-based metal complexes as multifunctional candidates for medicinal and materials chemistry applications.

Suggested Citation

  • Jalpa G. Gadara & Manhar V. Parsania, 2026. "Transition Metal Complexes of an Adamantane-Containing Schiff Base Ligand: Synthesis, Structural Characterization and Bioactivity," International Journal of Scientific Research in Chemistry, International Journal of Scientific Research in Chemistry, vol. 11(1), pages 20-25, January.
    • Handle: RePEc:cuo:ijsrch:v11:y2026:i1:id:78
    DOI: 10.32628/IJSRCH261114
    Note: Article URL: https://ijsrch.com/home/article/view/IJSRCH261114
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