IDEAS home Printed from https://ideas.repec.org/a/caa/jnlvet/v61y2016i10id24-2016-vetmed.html
   My bibliography  Save this article

Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model

Author

Listed:
  • J. Vokurka

    (Clinic of Dentistry, St. Anne's Faculty Hospital, Brno, Czech Republic)

  • E. Gopfert

    (Veterinary Research Institute, Brno, Czech Republic)

  • M. Blahutkova

    (Veterinary Research Institute, Brno, Czech Republic)

  • E. Buchalova

    (Clinic of Dentistry, St. Anne's Faculty Hospital, Brno, Czech Republic)

  • M. Faldyna

    (Veterinary Research Institute, Brno, Czech Republic)

Abstract

Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are platelet concentrates which have been used to improve healing and regeneration of damaged tissues. The concentration of growth factors greatly influences the final outcome of the treatment. For studying the effects of PRP and PRF, an animal model is required. The New Zealand White rabbit appears to be a good candidate for studying the features of these blood derivatives. This article presents for the first time the various preparation methods of blood derivatives with regard to concentration of growth factors - insulin-like growth factor, transforming growth factor and vascular endothelial growth factor. There was no statistically significant difference among the methods in the case of the first two factors. In the case of vascular endothelial growth factor, the lowest amount was detected in PRF. This study, even though performed on a limited number of animals, reports novel characterisation of the rabbit as an animal model for in vivo studies of the action of these blood derivatives.

Suggested Citation

  • J. Vokurka & E. Gopfert & M. Blahutkova & E. Buchalova & M. Faldyna, 2016. "Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 61(10), pages 567-570.
    • Handle: RePEc:caa:jnlvet:v:61:y:2016:i:10:id:24-2016-vetmed
    DOI: 10.17221/24/2016-VETMED
    as

    Download full text from publisher

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/24/2016-VETMED.html
    Download Restriction: free of charge
    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/24/2016-VETMED.pdf
    Download Restriction: free of charge
    File URL: https://libkey.io/10.17221/24/2016-VETMED?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlvet:v:61:y:2016:i:10:id:24-2016-vetmed. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.