IDEAS home Printed from https://ideas.repec.org/a/caa/jnlvet/v47y2002i10-11id5835-vetmed.html
   My bibliography  Save this article

Comparison of immune parameters in cows with normal and prolonged involution time of uterus

Author

Listed:
  • M. Levkut

    (University of Veterinary Medicine, Košice, Slovak Republic)

  • J. Pistl

    (University of Veterinary Medicine, Košice, Slovak Republic)

  • V. Revajová

    (University of Veterinary Medicine, Košice, Slovak Republic)

  • J. Chroma

    (University of Veterinary Medicine, Košice, Slovak Republic)

  • M. Levkutová

    (University of Veterinary Medicine, Košice, Slovak Republic)

  • V. Dávid

    (University of Veterinary Medicine, Košice, Slovak Republic)

Abstract

Indices of cellular immunity in postpartum Holsteincows with the normal (n = 9) and prolonged (n = 4) uterine involution time were evaluated. Peripheral white blood cells were isolated by lysis from postpartum animals. An indirect immunofluorescence method for staining and flow cytometric analysis was employed to determine the cell subpopulation of lymphocytes. The function assays were also used to examine the activity of lymphocytes and phagocytes. A significant decrease in the lymphocyte absolute number, and subpopulation of T (CD2+, CD4+, CD8+), and B (IgM+) cells in dams with postparturient complications and prolonged uterine involution time was observed. The quantitative changes of immune cells were accompanied by a significant decline of phagocyte functional activity in an iodo-nitro-tetrazolium reductase test and polyclonal lymphocyte activation to phytohemagglutinin in a leukocyte migration-inhibition assay. In conclusion, a significant decrease in the lymphocyte absolute number and subpopulation of T (CD2+, CD4+, CD8+), and B (IgM+) cells was observed and the host defense role of phagocytes and lymphocytes was impaired in cows with prolonged uterine involution, which can increase their susceptibility to infections.

Suggested Citation

  • M. Levkut & J. Pistl & V. Revajová & J. Chroma & M. Levkutová & V. Dávid, 2002. "Comparison of immune parameters in cows with normal and prolonged involution time of uterus," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 47(10-11), pages 277-282.
    • Handle: RePEc:caa:jnlvet:v:47:y:2002:i:10-11:id:5835-vetmed
    DOI: 10.17221/5835-VETMED
    as

    Download full text from publisher

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/5835-VETMED.html
    Download Restriction: free of charge
    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/5835-VETMED.pdf
    Download Restriction: free of charge
    File URL: https://libkey.io/10.17221/5835-VETMED?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to

    for a different version of it.

    More about this item

    Keywords

    ;
    ;
    ;
    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlvet:v:47:y:2002:i:10-11:id:5835-vetmed. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.