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Mannitol evaluated mineral absorption and bone retention in ovariectomized rats

Author

Listed:
  • Jin Xiao

    (College of Animal Science, Inner Mongolian Agricultural University, Hohhot, China)

  • Ei Sakaguchi

    (Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan)

  • Bin Lin Shi

    (College of Animal Science, Inner Mongolian Agricultural University, Hohhot, China)

Abstract

Indigestible sugars are used in food production and pharmaceutical industry due to their desirable properties. The effects of mannitol on Ca and Mg absorption and retention in ovariectomized rats were evaluated. Five weeks old ovariectomized Wistar rats were given Ca, Mg-deficient diet for 28 days then fed a control diet or 8% mannitol diets for another 28 days. Feaces were collected twice for 72h to measure mineral absorption. On day 56, rats were slaughtered and cecal parameters were observed. Femurs were collected to measure mineral levels. Results were shown that mineral absorption and femoral mineral was significantly increased by mannitol feeding. Cecal parameters were significantly altered after mannitol consumption. In conclusion, Ca and Mg absorption and their retention were improved by cecal fermentation of mannitol in ovariectomized rats.

Suggested Citation

  • Jin Xiao & Ei Sakaguchi & Bin Lin Shi, 2019. "Mannitol evaluated mineral absorption and bone retention in ovariectomized rats," Czech Journal of Food Sciences, Czech Academy of Agricultural Sciences, vol. 37(5), pages 319-324.
    • Handle: RePEc:caa:jnlcjf:v:37:y:2019:i:5:id:420-2017-cjfs
    DOI: 10.17221/420/2017-CJFS
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