IDEAS home Printed from https://ideas.repec.org/a/bla/biomet/v57y2001i1p294-301.html
   My bibliography  Save this article

Statistical Evaluation of the Regulatory Guidelines for Use of Furosemide in Race Horses

Author

Listed:
  • Karin K. Chu
  • Naisyin Wang
  • Scott Stanley
  • Noah D. Cohen

Abstract

Summary. The pharmacokinetic behavior of furosemide concentrations in performance horses is of great interest to the equine industry and equine researchers. Specifically, such information is useful for the evaluation of the existing guidelines in several racing jurisdictions and for the possible development of new guidelines for varying time periods after administration. We studied several approaches within the framework of nonlinear mixed effects models to increase the accuracy of evaluating these guidelines. Theoretical properties of the proposed methods were examined and the variances of the resulting estimators compared. Their numerical performances were further evaluated through simulations. Finally, we applied these methods to a furosemide concentration profile data set and used our findings to address certain important practical issues.

Suggested Citation

  • Karin K. Chu & Naisyin Wang & Scott Stanley & Noah D. Cohen, 2001. "Statistical Evaluation of the Regulatory Guidelines for Use of Furosemide in Race Horses," Biometrics, The International Biometric Society, vol. 57(1), pages 294-301, March.
    • Handle: RePEc:bla:biomet:v:57:y:2001:i:1:p:294-301
    DOI: 10.1111/j.0006-341X.2001.00294.x
    as

    Download full text from publisher

    File URL: https://doi.org/10.1111/j.0006-341X.2001.00294.x
    Download Restriction: no
    File URL: https://libkey.io/10.1111/j.0006-341X.2001.00294.x?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Cornelis J. Potgieter, 2020. "Density deconvolution for generalized skew-symmetric distributions," Journal of Statistical Distributions and Applications, Springer, vol. 7(1), pages 1-20, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bla:biomet:v:57:y:2001:i:1:p:294-301. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Wiley Content Delivery (email available below). General contact details of provider: http://www.blackwellpublishing.com/journal.asp?ref=0006-341X .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.