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Evaluation of EBNA-1 (epstein-barr virus nuclear antigen-1) gene prevalence in nasopharyngeal carcinoma in Vietnamese patients

Author

Listed:
  • Lao Duc Thuan

    (University of Science, Vietnam National University Ho Chi Minh City; Ho Chi Minh City Open University, Vietnam)

  • Nguyen Hoang Anh Tuan

    (University of Science, Vietnam National University Ho Chi Minh City, Vietnam)

  • Ngo Dong Kha

    (Ho Chi Minh City Open University, Vietnam)

  • Thieu Hong Hue

    (Ho Chi Minh City Open University, Vietnam)

  • Ho Ta Giap

    (Ho Chi Minh City Open University, Vietnam)

  • Nguyen Hai Chau

    (Ho Chi Minh City Open University, Vietnam)

  • Nguyen Huu Dung

    (Cho Ray Hospital, Ho Chi Minh City, Vietnam)

  • Le Huyen Ai Thuy

    (Ho Chi Minh City Open University, Vietnam)

Abstract

This study examined the presence of Epstein-Barr virus (EBV) in nasopharyngeal carcinoma (NPC) based on the detection of EBNA-1 (Epstein-Barr virus nuclear antigen-1) by Polymerase Chain Reaction (PCR), in Vietnamese population. Firstly, we systematically analyzed the mean of percentage weighted of the presence of EBNA-1 in previous relevant studies. Experimentally, 31 nasopharyngeal cancer biopsies and 20 healthy samples were enrolled in current to evaluate the frequency of candidate genes. As the results, the frequency of EBNA-1 was 77.42%, whereas, none of any cases of healthy samples were found to positive to target gene. The p value

Suggested Citation

  • Lao Duc Thuan & Nguyen Hoang Anh Tuan & Ngo Dong Kha & Thieu Hong Hue & Ho Ta Giap & Nguyen Hai Chau & Nguyen Huu Dung & Le Huyen Ai Thuy, 2016. "Evaluation of EBNA-1 (epstein-barr virus nuclear antigen-1) gene prevalence in nasopharyngeal carcinoma in Vietnamese patients," HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE - ENGINEERING AND TECHNOLOGY, HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, HO CHI MINH CITY OPEN UNIVERSITY, vol. 6(1), pages 3-10.
    • Handle: RePEc:bjw:techen:v:6:y:2016:i:1:p:3-10
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