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L-Proline Determination at Glassy Carbon Electrode

Author

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  • Dr. (Ms.) Phebe Kingsley

    (Department of Chemistry, N.E.S Ratnam College of Arts, Science and Commerce, (Autonomous) Bhandup 400 078)

  • Ms. Sakshi Sunil Jadhav

    (Department of Chemistry, N.E.S Ratnam College of Arts, Science and Commerce, (Autonomous) Bhandup 400 078)

Abstract

Voltammetric determination of L-Proline (L-Pro) using Cyclic voltammetry and Differential pulse voltammetry were recorded at glassy carbon electrode within the potential window 0.0 V and 2.4 V at the physiological pH. The reference and counter electrode used were Ag/AgCl and Pt wire, respectively.The effect of supporting electrolyte and concentration of electro active species on the interaction were also studied.The results demonstrate that the catalytic oxidation of L-Pro is diffusion-controlled and irreversible Under optimized conditions, the calibration curve for L-Pro concentration was linear in 〖3.5×10 〗^(-8) M to 〖1.5×10 〗^(-3) M with a low Limit of Quantification of 〖9.79×10 〗^(-9) M and a Limit of detection of 〖3.23×10 〗^(-8) M. It is shown that the prepared sensor provides a sensitive and rapid strategy for the detection of L-Proline.

Suggested Citation

  • Dr. (Ms.) Phebe Kingsley & Ms. Sakshi Sunil Jadhav, 2026. "L-Proline Determination at Glassy Carbon Electrode," International Journal of Research and Innovation in Applied Science, International Journal of Research and Innovation in Applied Science (IJRIAS), vol. 11(6), pages 503-510, June.
    • Handle: RePEc:bjf:journl:v:11:y:2026:i:6:p:503-510
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