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Formulation and Evaluation of Olopatadine Hydrochloride Opthalmic Solution

Author

Listed:
  • Akansha Athiya

    (M.Pharm., Vedic Institute of Pharmaceutical Education and Research, Sagar, Madhya Pradesh)

  • Deepak koshti

    (Professor, Vedic Institute of Pharmaceutical Education and Research, Sagar, Madhya Pradesh)

  • Ramdarshan Parashar

    (Professor, Vedic Institute of Pharmaceutical Education and Research, Sagar, Madhya Pradesh)

  • VaibhavRajoriya

    (Associate Professor, Vedic Institute of Pharmaceutical Education and Research, Sagar, MP)

  • YogeshSharma

    (Professor, Vedic Institute of Pharmaceutical Education and Research, Sagar, Madhya Pradesh)

  • Ajay Singh Thakur

    (Professor, Vedic Institute of Pharmaceutical Education and Research, Sagar, Madhya Pradesh)

Abstract

Olopatadine Hydrochloride is a selective histamine H1-receptor antagonist and mast cell stabilizer widely used in the treatment of allergic conjunctivitis. The present study aimed to formulate and evaluate a sterile ophthalmic solution of Olopatadine Hydrochloride with enhanced stability, safety, and patient compliance. The ophthalmic solution was prepared using suitable excipients, including buffering agents, tonicity adjusters, preservatives, and viscosity enhancers to achieve optimal physicochemical properties and ocular compatibility.

Suggested Citation

  • Akansha Athiya & Deepak koshti & Ramdarshan Parashar & VaibhavRajoriya & YogeshSharma & Ajay Singh Thakur, 2026. "Formulation and Evaluation of Olopatadine Hydrochloride Opthalmic Solution," International Journal of Research and Innovation in Applied Science, International Journal of Research and Innovation in Applied Science (IJRIAS), vol. 11(6), pages 3839-3859, June.
    • Handle: RePEc:bjf:journl:v:11:y:2026:i:6:p:3839-3859
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