IDEAS home Printed from https://ideas.repec.org/a/bjf/journl/v11y2026i3p155-165.html

Prevalence and Molecular Characterization of Antibiotic-Resistant Escherichia coli O157:H7 Isolated from Human and Poultry Faeces in the Federal Capital Territory, Nigeria

Author

Listed:
  • Okeke, O.C.

    (Directorate of Research and Analysis, Ministry of Foreign Affairs, Abuja)

  • Nafarnda, W.D.

    (Department of Veterinary Public Health and Preventive Medicine Faculty of Veterinary Medicine, University of Abuja)

  • Enem, S.I.

    (Department of Veterinary Public Health and Preventive Medicine Faculty of Veterinary Medicine, University of Abuja)

  • Ameh, J.A

    (Department of Veterinary Public Health and Preventive Medicine Faculty of Veterinary Medicine, University of Abuja)

  • Enefe, N.G

    (Department of Veterinary Public Health and Preventive Medicine Faculty of Veterinary Medicine, University of Abuja)

Abstract

This study accessed the prevalence and molecular characteristics of antibiotic-resistant Escherichia coli O157:H7 in humans and poultry within the Federal Capital Territory (FCT), Nigeria. A total prevalence of 9% was observed in humans, with 7.5% in Internally Displaced Persons (IDP) camps and 10.5% in hospitals, while poultry showed a prevalence of 0.8%. The isolates exhibited multiple antibiotic resistance, with 100% resistance to oxytetracycline in both human and poultry samples. Extended-Spectrum Beta-Lactamase (ESBL) enzymes were detected, and virulent genes including rfbE, eaeA, stx1, and stx2 were identified. Phylogenetic analysis revealed close genetic relationships between human and poultry isolates, suggesting possible cross-transmission and zoonotic potential. These findings highlight the urgent need for judicious antibiotic use, regular surveillance, and molecular monitoring to guide antimicrobial therapy and prevent outbreaks. The study underscores the importance of adopting a One Health approach to address antimicrobial resistance and safeguard public health.

Suggested Citation

  • Okeke, O.C. & Nafarnda, W.D. & Enem, S.I. & Ameh, J.A & Enefe, N.G, 2026. "Prevalence and Molecular Characterization of Antibiotic-Resistant Escherichia coli O157:H7 Isolated from Human and Poultry Faeces in the Federal Capital Territory, Nigeria," International Journal of Research and Innovation in Applied Science, International Journal of Research and Innovation in Applied Science (IJRIAS), vol. 11(3), pages 155-165, March.
    • Handle: RePEc:bjf:journl:v:11:y:2026:i:3:p:155-165
    as

    Download full text from publisher

    File URL: https://rsisinternational.org/journals/ijrias/uploads/vol11-iss3-pg155-165-202603_pdf.pdf
    Download Restriction: no
    File URL: https://rsisinternational.org/journals/ijrias/view/prevalence-and-molecular-characterization-of-antibiotic-resistant-escherichia-coli-o157-h7-isolated-from-human-and-poultry-faeces-in-the-federal-capital-territory-nigeria/
    Download Restriction: no
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bjf:journl:v:11:y:2026:i:3:p:155-165. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Dr. Renu Malsaria (email available below). General contact details of provider: https://rsisinternational.org/journals/ijrias/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.