IDEAS home Printed from https://ideas.repec.org/a/bjf/journl/v10y2025i7p665-672.html
   My bibliography  Save this article

Investigation of 44ti (N, P) and44 Ti (D, 2p) Reactions in the Production of 44sc for Theranostic Applications

Author

Listed:
  • Zubaida, G.H

    (Department of Physics, Yusuf Maitama Sule, Federal University of Education, Kano, Nigeria)

  • Koki, F.S

    (Department of Physics, Bayero University Kano Nigeria)

  • Ahmad, I.

    (Department of Physics, Bayero University Kano Nigeria)

Abstract

Sustainable use of nuclear medicine procedures for diagnosis and therapy of complex anomalies will continue to rely on the emergence of more radionuclides in the quest to achieve higher efficacy, higher image resolution or more efficient therapy – one of such radionuclides is Scandium-44, a positron emitter that holds the potential to propel the theranostics approach to higher levels. This paper investigates the 44Ti (n,p) and 44Ti (d-2p) reactions for the production of 44Sc using GEANT4, a C++ MC based simulation toolkit with a view to identify the more efficient route in terms of incident energy production cross sections The findings show that (n,p) reactions generated higher cross sections at threshold which declines with rising neutron energy. The (d,2p) reaction despite exhibiting lower cross sections also dispose a number of isomeric states posing challenge to optimization. Excitation functions of both reactions showed good agreement with both evaluated (ENDF) and experimental EXFOR datasets. As 44Sc (t1/2 = 4 h) is used for PET, and matched with 47Sc (t1/2 = 3.5 d) for theranostics approach, its ability to replace Gallium (t1/2 = 68 min) makes it possible to take the radionuclide to distant PET centers in addition to its use in planning and monitoring targeted radionuclide therapy of some radionuclides.

Suggested Citation

  • Zubaida, G.H & Koki, F.S & Ahmad, I., 2025. "Investigation of 44ti (N, P) and44 Ti (D, 2p) Reactions in the Production of 44sc for Theranostic Applications," International Journal of Research and Innovation in Applied Science, International Journal of Research and Innovation in Applied Science (IJRIAS), vol. 10(7), pages 665-672, July.
  • Handle: RePEc:bjf:journl:v:10:y:2025:i:7:p:665-672
    as

    Download full text from publisher

    File URL: https://www.rsisinternational.org/journals/ijrias/digital-library/volume-10-issue-7/665-672.pdf
    Download Restriction: no

    File URL: https://rsisinternational.org/journals/ijrias/articles/investigation-of-44ti-n-p-and44-ti-d-2p-reactions-in-the-production-of-44sc-for-theranostic-applications/
    Download Restriction: no
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bjf:journl:v:10:y:2025:i:7:p:665-672. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Dr. Renu Malsaria (email available below). General contact details of provider: https://rsisinternational.org/journals/ijrias/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.