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Methodological Standardization in Knee Joint Ultrasound: A Comprehensive Research Procedure

Author

Listed:
  • Kaneez Abbas

    (Athreya Medtech)

  • M. Asif Ali

    (DeCure Center)

  • Alireza Mobasseri

    (Shahroud University of Medical Sciences)

  • Mahdi Khanbabazadeh

    (Chiro-Care Chiropractic Clinic)

  • Bala Balaguru

    (Athreya Medtech)

  • Hadi Khazaei

    (Athreya Medtech)

Abstract

Background: Knee ultrasonography is a key diagnostic and research tool for evaluating joint effusion, synovitis, tendon, and ligament integrity. Despite its widespread use, methodological inconsistencies across studies-ranging from patient positioning to probe settings-limit reproducibility and cross-study comparability. Objective: To outline a standardized, evidence-based procedure for knee joint ultrasound suitable for research applications, aligning with international guidelines to ensure methodological rigor and reproducibility. Methods: A comprehensive research framework was developed incorporating standardized participant selection, equipment calibration, scanning parameters, patient positioning, and both static and dynamic maneuvers Results: Implementing standardized ultrasound protocols minimizes measurement variability, improves the accuracy of synovial and vascularity assessment, and enhances longitudinal monitoring of therapeutic responses. Conclusion: Methodological standardization in knee ultrasound strengthens data validity, promotes reproducibility, and facilitates integration of imaging biomarkers into clinical and translational musculoskeletal research. The outlined framework serves as a template for future multicenter and longitudinal ultrasound studies.

Suggested Citation

  • Kaneez Abbas & M. Asif Ali & Alireza Mobasseri & Mahdi Khanbabazadeh & Bala Balaguru & Hadi Khazaei, 2025. "Methodological Standardization in Knee Joint Ultrasound: A Comprehensive Research Procedure," International Journal of Research and Innovation in Applied Science, International Journal of Research and Innovation in Applied Science (IJRIAS), vol. 10(10), pages 2022-2036, October.
    • Handle: RePEc:bjf:journl:v:10:y:2025:i:10:p:2022-2036
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