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Pharmacological Evaluation of Imperata Cylindrica Crude Extract as Anti-Angiogenic Potential: Network Pharmacology, Molecular Docking Prediction with ADMET Analysis and CAM Assay Visualization

Author

Listed:
  • Sheemaiah Kylle L. Hasim

    (STEM Department, Carlos P. Garcia Senior High School, Davao City)

  • Mary Chris M. Castillo

    (STEM Department, Carlos P. Garcia Senior High School, Davao City)

  • Riza Jane T. Andig

    (STEM Department, Carlos P. Garcia Senior High School, Davao City)

  • Julio Raymundo M. Pasagui

    (STEM Department, Carlos P. Garcia Senior High School, Davao City)

  • Judie L. Velasco

    (STEM Department, Carlos P. Garcia Senior High School, Davao City)

Abstract

This study investigated the anti-angiogenic potential of Imperata cylindrica (cogon grass) leaf extract through an integrated network pharmacology–guided in silico approach coupled with in vivo validation, focusing on the multi-target behavior of its bioactive compounds. Given the central role of angiogenesis in tumor growth and metastasis, identifying plant-derived compounds capable of modulating angiogenic pathways remains a strategic priority in cancer research.

Suggested Citation

  • Sheemaiah Kylle L. Hasim & Mary Chris M. Castillo & Riza Jane T. Andig & Julio Raymundo M. Pasagui & Judie L. Velasco, 2026. "Pharmacological Evaluation of Imperata Cylindrica Crude Extract as Anti-Angiogenic Potential: Network Pharmacology, Molecular Docking Prediction with ADMET Analysis and CAM Assay Visualization," International Journal of Research and Scientific Innovation, International Journal of Research and Scientific Innovation (IJRSI), vol. 13(2), pages 616-648, February.
    • Handle: RePEc:bjc:journl:v:13:y:2026:i:2:p:616-648
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