IDEAS home Printed from https://ideas.repec.org/a/bjc/journl/v12y2025i15p16-21.html
   My bibliography  Save this article

Antibiotic Resistance Patterns in Enteric Fever Management: A Cross-Sectional Study in Kaduna Metropolis, Nigeria

Author

Listed:
  • Sani A. Mohammed

    (Department of Clinical Pharmacology and Therapeutics, Kaduna State University, Kaduna, Nigeria)

  • Yusuf Akande

    (Grants and Collaborations Office, Federal Neuropsychiatric Hospital, Kaduna, Nigeria)

  • Mohammed N. Danjuma

    (Department of Pharmacology and Therapeutics, Ahmadu Bello University Zaria, Nigeria)

  • Sherifat B. Anafi

    (Department of Pharmacology and Therapeutics, Ahmadu Bello University Zaria, Nigeria)

Abstract

This study examined antibiotic susceptibility patterns of bacteria isolated from patients with suspected enteric fever in Kaduna Metropolis, Nigeria, and compared the findings with global trends. Blood samples from 175 symptomatic patients were analyzed, revealing Staphylococcus species in 47.4% and Salmonella Typhi in 5.7% of isolates. All S. Typhi isolates were 100% susceptible to cephalosporins, chloramphenicol, fluoroquinolones, macrolides, and aminoglycosides, while reduced susceptibility to penicillins and cotrimoxazole was noted. MIC and MBC data highlighted chloramphenicol and trimethoprim-sulfamethoxazole as effective treatment options. The results confirm the efficacy of key antibiotics for enteric fever management in Kaduna, mirroring patterns in sub-Saharan Africa and Asia. However, diminished susceptibility to some drugs underscores the need for antimicrobial stewardship to curb resistance and inform local treatment guidelines.

Suggested Citation

  • Sani A. Mohammed & Yusuf Akande & Mohammed N. Danjuma & Sherifat B. Anafi, 2025. "Antibiotic Resistance Patterns in Enteric Fever Management: A Cross-Sectional Study in Kaduna Metropolis, Nigeria," International Journal of Research and Scientific Innovation, International Journal of Research and Scientific Innovation (IJRSI), vol. 12(15), pages 16-21, January.
    • Handle: RePEc:bjc:journl:v:12:y:2025:i:15:p:16-21
    as

    Download full text from publisher

    File URL: https://www.rsisinternational.org/journals/ijrsi/digital-library/volume-12-issue-15/16-21.pdf
    Download Restriction: no
    File URL: https://rsisinternational.org/journals/ijrsi/articles/antibiotic-resistance-patterns-in-enteric-fever-management-a-cross-sectional-study-in-kaduna-metropolis-nigeria/
    Download Restriction: no
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bjc:journl:v:12:y:2025:i:15:p:16-21. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Dr. Renu Malsaria (email available below). General contact details of provider: https://rsisinternational.org/journals/ijrsi/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.