Seroprevalence of Herpes Simplex Virus Type 2 Antibodies among HIV- Infected Individuals Attending Lautech Teaching Hospital, Ogbomoso, Oyo State

Background: Herpes Simplex Virus type 2 (HSV-2) is an opportunistic infection of public health concern globally among people living with HIV (PLWHIV). This study focused on the prevalence of and risk factors for HSV among PLWHIV to help them live a healthier life. Methods: A cross-sectional study was conducted at the Retroviral Clinic of LAUTECH Teaching Hospital, Ogbomosho, between December 2021 and June 2022. A total of 208 consenting individuals were enrolled in the study. Type-specific anti-HSV-2 IgG and IgM antibodies were detected using ELISA. Risk factors and the prevalence of HSV type 2 were analyzed using SPSS version 23. Results: The prevalence rates of HSV-2 IgG among 104 PLWHIV and 104 non-HIV were 40.4% and 0%, respectively. The prevalence of HSV-2 IgM among 104 PLWHIV and 104 non-HIV was 7.7% and 4.8%, respectively. A significant HSV-2 prevalence (3.8%, P=0.049) was reported among those with one or more sexual partners. The percentages of females and males who were positive for HSV-2 IgG were 40.0% and 41.0%, respectively. Conclusion: HSV-2 infection remains a significant comorbidity among PLWHIV. Increased awareness, screening, and prevention efforts are essential to reduce the dual burden.