Venomous Encounters: A Study of Box Jellyfish (Chironex Fleckeri) In Philippine Coastal Ecosystems

Box jellyfish Chironex fleckeri stings pose a serious public health threat in the Philippines. Cases were reported to have caused dermal necrosis and infections. The nephrotoxicity of the venom of Chironex fleckeri has been attributed to hemolysis, oxidative stress, and inflammation, which lead to acute kidney injury. Despite numerous studies on the mechanisms involved with the venom, not much is known to this date about its overall contribution to either treatment efficacy or kidney dysfunction. A descriptive review of mechanisms of venom, diagnostic approaches, and treatments in the Philippine setting will help highlight the deficit in pertinent public health policies. Chironex fleckeri is likely to be found in the coastal and estuarine areas of the Philippines. Distribution is influenced by seasonal water temperature and salinity, mirroring conditions found in its native Australian waters. Such risk factors can include the physical characteristics of this jellyfish, a transparent, cube-shaped bell with long, venomous tentacles, which will deliver potent venom. Knowing where and what, in terms of physical characteristics, puts into perspective all the risk factors for better patient outcomes.