IDEAS home Printed from https://ideas.repec.org/a/bjc/journl/v11y2024i2p215-223.html
   My bibliography  Save this article

Amino Acid Profile, Total Protein and Histological Changes in Female Wistar Rats After Administration of Dichloromethane Extract of Heterotis Rotundifolia Leaves on Dermal Wound

Author

Listed:
  • Ogechukwu E. Ezim

    (Department of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Rivers State, Nigeria)

  • Jane A. Agwu

    (Department of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Rivers State, Nigeria)

Abstract

The study investigated the amino acid and wound healing potentials of the leaves of Heterotis rotundifolia. Amino acid analysis was performed using HPLC. Total protein level, body weight and histology were studied. Excision wound(2cm) was induced on the dorsal skin of 75 wistar rats (176-308g) divided into five groups of fifteen animals: control, 0.1g Vaseline, 0.1g gentamicin (reference drug), 0.1g extract+0.1g Vaseline (HRE1) and 0.2g extract+0.1g Vaseline (HRE2). At the end of days 1, 7, 14 and 21, rats were sacrificed and blood was collected for wound healing parameters while wound surface was taken for histology. The result revealed a higher total protein level of HRE1 with a significant difference (p

Suggested Citation

  • Ogechukwu E. Ezim & Jane A. Agwu, 2024. "Amino Acid Profile, Total Protein and Histological Changes in Female Wistar Rats After Administration of Dichloromethane Extract of Heterotis Rotundifolia Leaves on Dermal Wound," International Journal of Research and Scientific Innovation, International Journal of Research and Scientific Innovation (IJRSI), vol. 11(2), pages 215-223, February.
    • Handle: RePEc:bjc:journl:v:11:y:2024:i:2:p:215-223
    as

    Download full text from publisher

    File URL: https://www.rsisinternational.org/journals/ijrsi/digital-library/volume-11-issue-2/215-223.pdf
    Download Restriction: no
    File URL: https://rsisinternational.org/journals/ijrsi/articles/amino-acid-profile-total-protein-and-histological-changes-in-female-wistar-rats-after-administration-of-dichloromethane-extract-of-heterotis-rotundifolia-leaves-on-dermal-wound/
    Download Restriction: no
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bjc:journl:v:11:y:2024:i:2:p:215-223. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Dr. Renu Malsaria (email available below). General contact details of provider: https://www.rsisinternational.org/journals/ijrsi/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.