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Performance of Procalcitonin and Reactive Protein-C in the Diagnosis of Early Neonatal Infection At the C.H.U of Brazzaville

Author

Listed:
  • Jeanne Gambomi Kibah

    (Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo. 2Biochemistry Department, CHU, Brazzaville, Congo)

  • franck Arnaud Kinsangou Moukobolo

    (Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo. 2Biochemistry Department, CHU, Brazzaville, Congo)

  • Koumou Fylla Onanga

    (Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo. 2Biochemistry Department, CHU, Brazzaville, Congo)

  • Rod Ibara-Okadandé

    (Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo. 2Biochemistry Department, CHU, Brazzaville, Congo)

  • Nanikaly Moyen

    (Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo.3Service de Bactériologie-Immunologie-Virologie CHU, Brazzaville Congo)

  • Etienne Moukoundjimobe

    (Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo.4Lomo University of research, Kinshasa, DRC)

  • Gaston Bowassa Ekouya

    (Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo.5Neonatology Department, Centre Hospitalier Universitaire, Brazzaville, Congo)

Abstract

The aim of this study was to evaluate the performance of procalcitonin and C-reactive protein in the diagnosis of early neonatal infection at Brazzaville University Hospital. This is a cross-sectional analytical study of 43 patients followed up in the Neonatology Department of the Brazzaville University Hospital Centre between July and November 2021. Procalcitonin, C-reactive protein and blood cultures were positive in 90.7%, 37.2% and 60% of cases respectively. The p-value was significant for procalcitonin (p = 0.001). The performance criteria for the biomarkers studied evolved in the opposite direction. However, the sensitivities of procalcitonin and C-reactive protein were 100% and 42.3% respectively, and the specificities of these biomarkers were 70.6% and 23.5% respectively. Procalcitonin cannot be used as the sole marker of neonatal infection ; it must always be combined with C-reactive protein.

Suggested Citation

  • Jeanne Gambomi Kibah & franck Arnaud Kinsangou Moukobolo & Koumou Fylla Onanga & Rod Ibara-Okadandé & Nanikaly Moyen & Etienne Moukoundjimobe & Gaston Bowassa Ekouya, 2025. "Performance of Procalcitonin and Reactive Protein-C in the Diagnosis of Early Neonatal Infection At the C.H.U of Brazzaville," International Journal of Latest Technology in Engineering, Management & Applied Science, International Journal of Latest Technology in Engineering, Management & Applied Science (IJLTEMAS), vol. 14(5), pages 1018-1021, May.
    • Handle: RePEc:bjb:journl:v:14:y:2025:i:5:p:1018-1021
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