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Current Status of Induction Chemotherapy in Locally Advanced Nasopharyngeal Carcinoma

Author

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  • Xinhao Chen

    (Department of Oncology, Laboratory of Immunity, Inflammation & Cancer, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China)

  • Runtian Xiao

    (Department of Oncology, Laboratory of Immunity, Inflammation & Cancer, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China)

  • Tao Zhang

    (Department of Oncology, Laboratory of Immunity, Inflammation & Cancer, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China)

Abstract

Nasopharyngeal carcinoma (NPC) has a unique endemic distribution in the world, with the highest incidence rate in South China, Southeast Asia and North Africa. About 70% of newly diagnosed nasopharyngeal carcinoma patients suffer from locally advanced diseases. The current methods of radiotherapy and chemotherapy include synchronous radiotherapy and chemotherapy, induction chemotherapy, and adjuvant chemotherapy. Induction chemotherapy has better tolerance, so higher drug concentrations can be used to improve the survival rate of locally advanced nasopharyngeal carcinoma patients. Induction chemotherapy can eliminate micro metastatic diseases early. This article provides a review of the application of induction chemotherapy in the treatment of locally advanced nasopharyngeal carcinoma.

Suggested Citation

  • Xinhao Chen & Runtian Xiao & Tao Zhang, 2025. "Current Status of Induction Chemotherapy in Locally Advanced Nasopharyngeal Carcinoma," Journal of Innovations in Medical Research, Paradigm Academic Press, vol. 4(2), pages 59-65, April.
  • Handle: RePEc:bdz:joimer:v:4:y:2025:i:2:p:59-65
    DOI: 10.63593/JIMR.2788-7022.2025.04.007
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