IDEAS home Printed from https://ideas.repec.org/a/bdz/joimer/v4y2025i2p26-28.html

Mean Platelet Volume and Cancer-Associated Deep Vein Thrombosis

Author

Listed:
  • A. Guiga

    (Department of Internal Medicine, Farhat Hached University Hospital, Faculty of Medicine, University of Sousse, 4002 Sousse, Tunisia)

  • M. Krifa

    (Department of Internal Medicine, Farhat Hached University Hospital, Faculty of Medicine, University of Sousse, 4002 Sousse, Tunisia)

  • A. Amara

    (Department of Family and Community Medicine, Faculty of Medicine, University of Sousse, 4002 Sousse, Tunisia)

  • M. Thabet

    (Department of Internal Medicine, Farhat Hached University Hospital, Faculty of Medicine, University of Sousse, 4002 Sousse, Tunisia)

  • W. BenYahia

    (Department of Internal Medicine, Farhat Hached University Hospital, Faculty of Medicine, University of Sousse, 4002 Sousse, Tunisia)

  • A. Atig

    (Department of Internal Medicine, Farhat Hached University Hospital, Faculty of Medicine, University of Sousse, 4002 Sousse, Tunisia)

  • C. Zedini

    (Department of Family and Community Medicine, Faculty of Medicine, University of Sousse, 4002 Sousse, Tunisia)

  • N. Ghannouchi

    (Department of Internal Medicine, Farhat Hached University Hospital, Faculty of Medicine, University of Sousse, 4002 Sousse, Tunisia)

Abstract

Background: Deep vein thrombosis (DVT) is a common and serious complication in cancer patients, primarily driven by malignancy-induced hypercoagulability and systemic inflammation. Mean platelet volume (MPV), a hematological parameter reflecting platelet activation and inflammatory status, has been proposed as a potential marker for thromboembolic risk stratification in oncology. Objective: This retrospective study aimed to assess the association between MPV and DVT in patients with underlying cancer. Methods: We analyzed MPV levels in a cohort of 102 patients diagnosed with DVT, including 18 individuals with active malignancy. Results: Although MPV values were slightly elevated in cancer patients compared to non-cancer patients, the difference did not reach statistical significance (p = 0.86). Conclusion: Our findings suggest that MPV is not a reliable biomarker for cancer-associated DVT. Further studies exploring alternative hematological and inflammatory markers are warranted to improve risk assessment in this high-risk population.

Suggested Citation

  • A. Guiga & M. Krifa & A. Amara & M. Thabet & W. BenYahia & A. Atig & C. Zedini & N. Ghannouchi, 2025. "Mean Platelet Volume and Cancer-Associated Deep Vein Thrombosis," Journal of Innovations in Medical Research, Paradigm Academic Press, vol. 4(2), pages 26-28, April.
    • Handle: RePEc:bdz:joimer:v:4:y:2025:i:2:p:26-28
    DOI: 10.63593/JIMR.2788-7022.2025.04.004
    as

    Download full text from publisher

    File URL: https://www.paradigmpress.org/jimr/article/view/1594/1422
    Download Restriction: no
    File URL: https://libkey.io/10.63593/JIMR.2788-7022.2025.04.004?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Keywords

    ;
    ;
    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bdz:joimer:v:4:y:2025:i:2:p:26-28. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Editorial Office (email available below). General contact details of provider: https://www.paradigmpress.org/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.