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Modulatory Effects of Aqueous Moringa Olifera Extract in Lead Mediated Endometriosis in Wistar Rats

Author

Listed:
  • Gabriel Idoko

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

  • Peter Onoja

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

  • Paul Beega

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

  • Vershima Kiekwe

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

  • Thaedeus Aende

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

  • Moses Mlumun

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

  • Paul Omirida

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

  • Gabriel Akunna

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

  • Linus Saalu

    (Department of Anatomy, College of Health Sciences, Benue State University, Makurdi)

Abstract

Context: The study aims to evaluate the modulatory effect of an aqueous extract of Moringa olifera on lead-mediated endometriosis in Wistar rats. Settings and Design: Twenty-five female Wistar rats were used for the study. The rats were divided into five groups, each containing five rats, and were treated daily for fourteen days. Group I (Control) was administered 5ml/Kg of distilled water per oral (PO), Group II was given 50mg/Kg of Lead PO, Group III was given 50mg/Kg Lead and 100mg/Kg of aqueous Moringa olifera extract (AMOE), Group IV received 50mg/Kg Lead plus 200mg/Kg AMOE while Group V received 50mg Lead plus 300mg AMOE PO. Results: At the end of the experiment, there was decreased estrogen level across the groups with only group II being significant (P

Suggested Citation

  • Gabriel Idoko & Peter Onoja & Paul Beega & Vershima Kiekwe & Thaedeus Aende & Moses Mlumun & Paul Omirida & Gabriel Akunna & Linus Saalu, 2024. "Modulatory Effects of Aqueous Moringa Olifera Extract in Lead Mediated Endometriosis in Wistar Rats," Journal of Innovations in Medical Research, Paradigm Academic Press, vol. 3(2), pages 58-74, June.
    • Handle: RePEc:bdz:joimer:v:3:y:2024:i:2:p:58-74
    DOI: 10.56397/JIMR/2024.06.09
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