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Characterization of Three-Dimensional Structures of Collagen Extracted from the Umbilical-Placental Complex for Applications in Oral-Maxillofacial Surgery

Author

Listed:
  • Mariana JIAN
  • Oleg SOLOMON
  • Andrei MOSTOVEI
  • Ovidiu Cristian OPREA
  • Ludmila MOTELICA
  • Ana-Maria NACU
  • Vitalie COBZAC
  • Denisa FICAI
  • Anton FICAI
  • Viorel NACU

Abstract

This paper is focused on the study of the three-dimensional structures of collagen extracted from the umbilical-placental complex with the aim of use in oral-maxillofacial surgery. Collagen was extracted from the umbilical-placental complex by a modified enzymatic method that involves initial purification with different surfactants to remove blood and cellular components and ensure non-immunogenicity. The null hypothesis of the concerned works consists in the fact that the surfactants used do not act on the collagen structures. Three-dimensional collagen structures were developed by the lyophilization process and were analyzed by scanning electron microscopy, Young's modulus (elasticity), thermogravimetry and Fourier transform infrared spectroscopy and microscopy.

Suggested Citation

  • Mariana JIAN & Oleg SOLOMON & Andrei MOSTOVEI & Ovidiu Cristian OPREA & Ludmila MOTELICA & Ana-Maria NACU & Vitalie COBZAC & Denisa FICAI & Anton FICAI & Viorel NACU, 2024. "Characterization of Three-Dimensional Structures of Collagen Extracted from the Umbilical-Placental Complex for Applications in Oral-Maxillofacial Surgery," Intellectus, State Agency on Intellectual Property (AGEPI), issue 1, pages 179-188, July.
    • Handle: RePEc:awf:journl:y:2024:i:1:p:179-188
    DOI: 10.56329/1810-7087.24.1.17
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