IDEAS home Printed from https://ideas.repec.org/a/asi/joasrj/v6y2016i3p41-47id3757.html

An Update on New Vaccines for Tuberculosis

Author

Listed:
  • Sumera, Afshan

    (Lecturer, Pathology Department, School of Medicine, International Medical University, Kuala Lumpur Malaysia)

  • Inn, Leong Chia

    (Student Bachelor of Science (Honours) Biomedical Science Programme, International Medical University, Kuala Lumpur Malaysia)

  • Barua, Ankur

    (Senior Lecturer, Community Medicine Department, School of Medicine, International Medical University, Kuala Lumpur Malaysia)

Abstract

Tuberculosis (TB) is one of the most common and deadly communicable diseases in the world, infecting approximately one-third of the total human race. The number of drug-resistant TB cases are increasing. The spectrum of resistance varies from single to multidrug and from multidrug to total drug resistance varieties. Human Immunodeficiency Virus (HIV) infection is also responsible for the recent re-emergence of tuberculosis infection worldwide. When drugs are becoming ineffective against Mycobacterium tuberculosis, there is a need to focus more on preventive strategies. Though Bacillus Calmette–Guérin (BCG) vaccine is efficient in preventing miliary and meningeal tuberculosis in children, it is not effective against pulmonary tuberculosis. For prevention of pulmonary tuberculosis, development of new vaccines is the need of time. Several new vaccines are under clinical trials either to replace old BCG or act as a booster for the current BCG vaccine. New vaccines include live Mycobacterial vaccines, its subunit, live vector-based vaccines and killed whole or fragmented vaccines. This review recaps the status of development of pre-clinical tuberculosis vaccines.

Suggested Citation

  • Sumera, Afshan & Inn, Leong Chia & Barua, Ankur, 2016. "An Update on New Vaccines for Tuberculosis," Journal of Asian Scientific Research, Asian Economic and Social Society, vol. 6(3), pages 41-47.
    • Handle: RePEc:asi:joasrj:v:6:y:2016:i:3:p:41-47:id:3757
    DOI: 10.18488/journal.2/2016.6.3/2.3.41.47
    as

    Download full text from publisher

    File URL: https://archive.aessweb.com/index.php/5003/article/view/3757
    Download Restriction: no
    File URL: https://archive.aessweb.com/index.php/5003/article/view/3757/5932
    Download Restriction: no
    File URL: https://libkey.io/10.18488/journal.2/2016.6.3/2.3.41.47?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Keywords

    ;
    ;
    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:asi:joasrj:v:6:y:2016:i:3:p:41-47:id:3757. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Robert Allen (email available below). General contact details of provider: https://archive.aessweb.com/index.php/5003/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.