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Impact of Ethanolic Extract of Tecoma stans and Costus afer Leaves on Lipid Profile Status of Streptozotocin Induced Diabetic Wistar Rats

Author

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  • Ini Ekpe
  • Esua Orok Udosen
  • Dennis Amaechi
  • Benjamin Yisa

Abstract

The lipid profile status of streptozotocin induced diabetic rats treated with ethanolic extract of Tecoma stans and Costus afer leaves using seventy (70) male wistar rats divided into five (5) parallel group consisting of diabetic (DC) and non diabetic (ND) groups of seven (7) rats per group. Group I received placebo (Control) Group II received insulin (humulin 5mg/kg body weight) Group II received Ts 250mg/kg Body weight) Group IV, received Ca (200mg/kg Body weight) Group V received combined extracts TS (150mg/kg body weight) A and a (100mg/kg body weight). The extracts were administered orally while insulin was subcutaneously. The treatment lasted for 21 days after which the animals were sacrificed and whole blood was collected for biochemical analysis. There was no significant increase in total cholesterol among insulin, Tecoma stans and combined therapy when compared to NC. HDL-C was significantly (P

Suggested Citation

  • Ini Ekpe & Esua Orok Udosen & Dennis Amaechi & Benjamin Yisa, 2018. "Impact of Ethanolic Extract of Tecoma stans and Costus afer Leaves on Lipid Profile Status of Streptozotocin Induced Diabetic Wistar Rats," International Journal of Sciences, Office ijSciences, vol. 7(08), pages 16-20, August.
    • Handle: RePEc:adm:journl:v:7:y:2018:i:8:p:16-20
    DOI: 10.18483/ijSci.1740
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