Development and Assessment of aHerbal Cream Enriched with Wild Rue, Winter CherryandTurmeric for Skin Disease Treatment

Skin disease and skin infections are mostly caused due to physical injuries or bacterial infections. Herbal cream is preferred over other creams due to less side effects of allergic reactions and itching. In the present study,three types of creams (F1, F2andF3) were prepared by adding different quantities of methanolic extract in dry powder of seeds of wild rue, winter cherryandthe rhizome of turmeric and compared them with standard cream Betadine. The formulations formed were evaluated physically by examining themvisually for their color, odor, homogeneity, spreadability,type of smear, emulsion, viscosity and uniformity of weight and skin irritancy of all the three herbal formulations (F1, F2andF3) and marketed medical betadine cream and noted on 5 different days i.e., 0, 5, 10, 15 and 20 days. The maximum percentage yield was shown by F1 i.e., 42.37% containing 30g turmericpowder and 60 ml methanol. While the lowest i.e., 35.69% wasshown by F3 consistingof 50g winter cherry powder and 100 ml methanol. The maximum and minimum antibacterial activity wasexhibited by formulation F1 and standard cream at 1.5 mg/ml and 0.5 mg/ml respectively. The creams were oil in water-basedand there was no irritation on the skin. This study showed that herbal creams contain natural ingredients that help to improve and satisfy customers because they have feweradverse effects than synthetic products.