The Health Utilities Index (HUI®) System for Assessing Health-Related Quality of Life in Clinical Studies
AbstractPurpose. The paper reviews the Health Utilities Index (HUI®) as a means to describe health status and obtain utility scores reflecting health-related quality of life (HRQL). Materials. The HUI Mark 2 (HUI2) and Mark 3 (HUI3) classification and scoring systems are described. The methods used to estimate multi-attribute utility functions for HUI2 and HUI3 are reviewed. The use of HUI in clinical studies for a wide variety of conditions in a large number of countries is illustrated. Principal Findings. HUI provides a comprehensive description of the health status of subjects in clinical studies. HUI has been shown to be a reliable, responsive and valid measure in a wide variety of clinical studies. Utility scores provide an overall assessment of the HRQL of patients. Utility scores are also useful in cost-utility analyses and related studies. General population norm data are available. The widespread use of HUI facilitates the interpretation of results and permits comparisons. Conclusions. HUI is a useful tool for assessing health status and HRQL in clinical studies.
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Bibliographic InfoPaper provided by Centre for Health Economics and Policy Analysis (CHEPA), McMaster University, Hamilton, Canada in its series Centre for Health Economics and Policy Analysis Working Paper Series with number 2001-02.
Length: 56 pages
Date of creation: 2001
Date of revision:
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clinical studies; cost-effectiveness analysis; cost-utility analysis; economic evaluation; health-related quality of life; health status; Health Utilities Index; HUI; QALY; utility;
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