IDEAS home Printed from https://ideas.repec.org/p/aiz/louvad/2021030.html
   My bibliography  Save this paper

A spline-based time-varying reproduction number for modelling epidemiological outbreaks

Author

Listed:
  • Pircalabelu, Eugen

    (Université catholique de Louvain, LIDAM/ISBA, Belgium)

Abstract

We develop in this manuscript a method for performing estimation and inference for the reproduction number of an epidemiological outbreak. The estimator is time-dependent and uses spline modeling to adapt to changes in the outbreak. This is accomplished by directly modeling the series of new infections as a function of time and subsequently using the derivative of the function to define a time-varying reproduction number.

Suggested Citation

  • Pircalabelu, Eugen, 2021. "A spline-based time-varying reproduction number for modelling epidemiological outbreaks," LIDAM Discussion Papers ISBA 2021030, Université catholique de Louvain, Institute of Statistics, Biostatistics and Actuarial Sciences (ISBA).
    • Handle: RePEc:aiz:louvad:2021030
    as

    Download full text from publisher

    File URL: https://dial.uclouvain.be/pr/boreal/en/object/boreal%3A244926/datastream/PDF_01/view
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Ruppert,David & Wand,M. P. & Carroll,R. J., 2003. "Semiparametric Regression," Cambridge Books, Cambridge University Press, number 9780521785167.
    2. Shinsuke Koyama & Taiki Horie & Shigeru Shinomoto, 2021. "Estimating the time-varying reproduction number of COVID-19 with a state-space method," PLOS Computational Biology, Public Library of Science, vol. 17(1), pages 1-18, January.
    3. Konstantinos Fokianos & Roland Fried, 2010. "Interventions in INGARCH processes," Journal of Time Series Analysis, Wiley Blackwell, vol. 31(3), pages 210-225, May.
    4. Ruppert,David & Wand,M. P. & Carroll,R. J., 2003. "Semiparametric Regression," Cambridge Books, Cambridge University Press, number 9780521780506.
    5. Inyoung Kim & Noah D. Cohen & Raymond J. Carroll, 2003. "Semiparametric Regression Splines in Matched Case-Control Studies," Biometrics, The International Biometric Society, vol. 59(4), pages 1158-1169, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Wu, Ximing & Sickles, Robin, 2018. "Semiparametric estimation under shape constraints," Econometrics and Statistics, Elsevier, vol. 6(C), pages 74-89.
    2. Julie Vercelloni & M Julian Caley & Mohsen Kayal & Samantha Low-Choy & Kerrie Mengersen, 2014. "Understanding Uncertainties in Non-Linear Population Trajectories: A Bayesian Semi-Parametric Hierarchical Approach to Large-Scale Surveys of Coral Cover," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-9, November.
    3. Otto-Sobotka, Fabian & Salvati, Nicola & Ranalli, Maria Giovanna & Kneib, Thomas, 2019. "Adaptive semiparametric M-quantile regression," Econometrics and Statistics, Elsevier, vol. 11(C), pages 116-129.
    4. Lee, Wang-Sheng & McKinnish, Terra, 2019. "Locus of control and marital satisfaction: Couple perspectives using Australian data," Journal of Economic Psychology, Elsevier, vol. 74(C).
    5. Becker, William, 2020. "Metafunctions for benchmarking in sensitivity analysis," Reliability Engineering and System Safety, Elsevier, vol. 204(C).
    6. Timothy K.M. Beatty & Erling Røed Larsen, 2005. "Using Engel curves to estimate bias in the Canadian CPI as a cost of living index," Canadian Journal of Economics/Revue canadienne d'économique, John Wiley & Sons, vol. 38(2), pages 482-499, May.
    7. Simon N. Wood, 2020. "Inference and computation with generalized additive models and their extensions," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 29(2), pages 307-339, June.
    8. Arthur Charpentier & Emmanuel Flachaire & Antoine Ly, 2017. "Econom\'etrie et Machine Learning," Papers 1708.06992, arXiv.org, revised Mar 2018.
    9. Hyunju Son & Youyi Fong, 2021. "Fast grid search and bootstrap‐based inference for continuous two‐phase polynomial regression models," Environmetrics, John Wiley & Sons, Ltd., vol. 32(3), May.
    10. Seebens, Holger, 2009. "Child Welfare and Old-Age Security in Female Headed Households in Tanzania," IZA Discussion Papers 3929, Institute of Labor Economics (IZA).
    11. Arūnas P. Verbyla & Joanne Faveri & John D. Wilkie & Tom Lewis, 2018. "Tensor Cubic Smoothing Splines in Designed Experiments Requiring Residual Modelling," Journal of Agricultural, Biological and Environmental Statistics, Springer;The International Biometric Society;American Statistical Association, vol. 23(4), pages 478-508, December.
    12. Michael Wegener & Göran Kauermann, 2017. "Forecasting in nonlinear univariate time series using penalized splines," Statistical Papers, Springer, vol. 58(3), pages 557-576, September.
    13. Dlugosz, Stephan & Mammen, Enno & Wilke, Ralf A., 2017. "Generalized partially linear regression with misclassified data and an application to labour market transitions," Computational Statistics & Data Analysis, Elsevier, vol. 110(C), pages 145-159.
    14. Bernhard Baumgartner & Daniel Guhl & Thomas Kneib & Winfried J. Steiner, 2018. "Flexible estimation of time-varying effects for frequently purchased retail goods: a modeling approach based on household panel data," OR Spectrum: Quantitative Approaches in Management, Springer;Gesellschaft für Operations Research e.V., vol. 40(4), pages 837-873, October.
    15. Clark, Andrew E. & Etilé, Fabrice, 2011. "Happy house: Spousal weight and individual well-being," Journal of Health Economics, Elsevier, vol. 30(5), pages 1124-1136.
    16. Zi Ye & Giles Hooker & Stephen P. Ellner, 2021. "Generalized Single Index Models and Jensen Effects on Reproduction and Survival," Journal of Agricultural, Biological and Environmental Statistics, Springer;The International Biometric Society;American Statistical Association, vol. 26(3), pages 492-512, September.
    17. Ferraccioli, Federico & Sangalli, Laura M. & Finos, Livio, 2022. "Some first inferential tools for spatial regression with differential regularization," Journal of Multivariate Analysis, Elsevier, vol. 189(C).
    18. Yichen Gao & Yu Zhang & Ximing Wu, 2015. "Penalized exponential series estimation of copula densities with an application to intergenerational dependence of body mass index," Empirical Economics, Springer, vol. 48(1), pages 61-81, February.
    19. Jaime Pinilla & Miguel Negrín, 2021. "Non-Parametric Generalized Additive Models as a Tool for Evaluating Policy Interventions," Mathematics, MDPI, vol. 9(4), pages 1-12, February.
    20. Marra Giampiero & Radice Rosalba, 2017. "A joint regression modeling framework for analyzing bivariate binary data in R," Dependence Modeling, De Gruyter, vol. 5(1), pages 268-294, December.

    More about this item

    Keywords

    reproduction number; time dependency; spline modeling; COVID-19;
    All these keywords.

    NEP fields

    This paper has been announced in the following NEP Reports:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:aiz:louvad:2021030. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Nadja Peiffer (email available below). General contact details of provider: https://edirc.repec.org/data/isuclbe.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.