Advanced Search
MyIDEAS: Login to save this article or follow this journal

Accommodating covariates in receiver operating characteristic analysis

Contents:

Author Info

  • Holly Janes

    ()
    (Fred Hutchinson Cancer Research Center)

  • Gary Longton

    ()
    (Fred Hutchinson Cancer Research Center)

  • Margaret S. Pepe

    ()
    (Fred Hutchinson Cancer Research Center)

Registered author(s):

    Abstract

    Classification accuracy is the ability of a marker or diagnostic test to discriminate between two groups of individuals, cases and controls, and is com- monly summarized by using the receiver operating characteristic (ROC) curve. In studies of classification accuracy, there are often covariates that should be incorporated into the ROC analysis. We describe three ways of using covariate information. For factors that affect marker observations among controls, we present a method for covariate adjustment. For factors that affect discrimination (i.e., the ROC curve), we describe methods for modeling the ROC curve as a function of covariates. Finally, for factors that contribute to discrimination, we propose combining the marker and covariate information, and we ask how much discriminatory accuracy improves (in incremental value) with the addition of the marker to the covariates. These methods follow naturally when representing the ROC curve as a summary of the distribution of case marker observations, standardized with respect to the control distribution. Copyright 2009 by StataCorp LP.

    Download Info

    If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
    File URL: http://www.stata-journal.com/article.html?article=st0155
    Download Restriction: no

    File URL: http://www.stata-journal.com/software/sj9-1/st0155/
    Download Restriction: no

    Bibliographic Info

    Article provided by StataCorp LP in its journal Stata Journal.

    Volume (Year): 9 (2009)
    Issue (Month): 1 (March)
    Pages: 17-39

    as in new window
    Handle: RePEc:tsj:stataj:v:9:y:2009:i:1:p:17-39

    Contact details of provider:
    Web page: http://www.stata-journal.com/

    Order Information:
    Web: http://www.stata-journal.com/subscription.html

    Related research

    Keywords: roccurve; comproc; rocreg; receiver operating characteristic analysis; ROC; covariates; sensitivity; specificity;

    References

    No references listed on IDEAS
    You can help add them by filling out this form.

    Citations

    Lists

    This item is not listed on Wikipedia, on a reading list or among the top items on IDEAS.

    Statistics

    Access and download statistics

    Corrections

    When requesting a correction, please mention this item's handle: RePEc:tsj:stataj:v:9:y:2009:i:1:p:17-39. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Christopher F. Baum) or (Lisa Gilmore).

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If references are entirely missing, you can add them using this form.

    If the full references list an item that is present in RePEc, but the system did not link to it, you can help with this form.

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.