IDEAS home Printed from https://ideas.repec.org/a/spr/scient/v126y2021i3d10.1007_s11192-020-03828-4.html
   My bibliography  Save this article

Major factors affecting biomedical cross-city R&D collaborations based on cooperative patents in China

Author

Listed:
  • Zuo-jun Dong

    (Zhejiang University of Technology)

  • Lan Xu

    (Zhejiang University of Technology)

  • Jia-hui Cheng

    (Zhejiang University of Technology)

  • Guo-jun Sun

    (Zhejiang University of Technology)

Abstract

Due to the fastidiousness of the industry, it has become absolutely necessary for the biomedical industry to seek innovative R&D collaborations in order to maintain high standards in technological advances as well as the array of products from various fields. The biomedical industry is seen to be focused in certain geographical locations; scientific research activities appear to cluster in cities or towns. Modern cities have the potential to play a crucial role in the national or regional innovation systems. Strengthening R&D collaborations between cities can bring about a perfect synergy that integrates various regional innovation systems. The cross-sectional co-patent data of the CNKI Medical and Health Technology Patent Database was taken up as a representation for the R&D collaboration. This paper investigates the spatial patterns of R&D collaborations between 224 Chinese cities and the major factors that influence biomedical cross-city R&D collaborations in China from 1990 to 2019. A spatial interaction model was used to examine how spatial, economic, technological and political factors affect cross-city R&D collaborations. The degree of supremacy shows that cross-city collaborative R&D activities occur mainly in favored regions, advanced municipalities and coastal regions. The mean intensity for interprovincial cross-city collaborations is higher than inter-provincial collaborations spanning over periods nearly six times the duration. The findings revealed that factors like spatial, economic, technological and political-bias definitely exert significant influences on the frequency of biomedical cross-city R&D collaborations. Specifically, the heterodyne dummy variable and the geographical distance variable have a certain degree of overlap, which has a significant impact on the cooperation frequency.

Suggested Citation

  • Zuo-jun Dong & Lan Xu & Jia-hui Cheng & Guo-jun Sun, 2021. "Major factors affecting biomedical cross-city R&D collaborations based on cooperative patents in China," Scientometrics, Springer;Akadémiai Kiadó, vol. 126(3), pages 1923-1943, March.
  • Handle: RePEc:spr:scient:v:126:y:2021:i:3:d:10.1007_s11192-020-03828-4
    DOI: 10.1007/s11192-020-03828-4
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s11192-020-03828-4
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1007/s11192-020-03828-4?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Adam B. Jaffe & Manuel Trajtenberg & Rebecca Henderson, 1993. "Geographic Localization of Knowledge Spillovers as Evidenced by Patent Citations," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 108(3), pages 577-598.
    2. Jarno Hoekman & Koen Frenken & Frank Oort, 2009. "The geography of collaborative knowledge production in Europe," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 43(3), pages 721-738, September.
    3. Chen, Kun & Kenney, Martin, 2007. "Universities/Research Institutes and Regional Innovation Systems: The Cases of Beijing and Shenzhen," World Development, Elsevier, vol. 35(6), pages 1056-1074, June.
    4. Roderik Ponds & Frank Van Oort & Koen Frenken, 2007. "The geographical and institutional proximity of research collaboration," Papers in Regional Science, Wiley Blackwell, vol. 86(3), pages 423-443, August.
    5. Liming Liang & Ling Zhu, 2002. "Major factors affecting China's inter-regional research collaboration: Regional scientific productivity and geographical proximity," Scientometrics, Springer;Akadémiai Kiadó, vol. 55(2), pages 287-316, August.
    6. Haitao Ma & Chuanglin Fang & Bo Pang & Guangdong Li, 2014. "The Effect of Geographical Proximity on Scientific Cooperation among Chinese Cities from 1990 to 2010," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-11, November.
    7. Zhang, Xiaobo & Kanbur, Ravi, 2005. "Spatial inequality in education and health care in China," China Economic Review, Elsevier, vol. 16(2), pages 189-204.
    8. Thomas Scherngell & Yuanjia Hu, 2011. "Collaborative Knowledge Production in China: Regional Evidence from a Gravity Model Approach," Regional Studies, Taylor & Francis Journals, vol. 45(6), pages 755-772.
    9. Hong, Wei, 2008. "Decline of the center: The decentralizing process of knowledge transfer of Chinese universities from 1985 to 2004," Research Policy, Elsevier, vol. 37(4), pages 580-595, May.
    10. Sheng-qiang Jiang & An-na Shi & Zhi-hang Peng & Xin Li, 2017. "Major factors affecting cross-city R&D collaborations in China: evidence from cross-sectional co-patent data between 224 cities," Scientometrics, Springer;Akadémiai Kiadó, vol. 111(3), pages 1251-1266, June.
    11. Xia Gao & Jiancheng Guan & Ronald Rousseau, 2011. "Mapping collaborative knowledge production in China using patent co-inventorships," Scientometrics, Springer;Akadémiai Kiadó, vol. 88(2), pages 343-362, August.
    12. Thomas Scherngell & Michael Barber, 2011. "Distinct spatial characteristics of industrial and public research collaborations: evidence from the fifth EU Framework Programme," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 46(2), pages 247-266, April.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Sheng-qiang Jiang & An-na Shi & Zhi-hang Peng & Xin Li, 2017. "Major factors affecting cross-city R&D collaborations in China: evidence from cross-sectional co-patent data between 224 cities," Scientometrics, Springer;Akadémiai Kiadó, vol. 111(3), pages 1251-1266, June.
    2. Kaihuang Zhang & Qinglan Qian & Yijing Zhao, 2020. "Evolution of Guangzhou Biomedical Industry Innovation Network Structure and Its Proximity Mechanism," Sustainability, MDPI, vol. 12(6), pages 1-20, March.
    3. Chen, Guanghua & Yang, Guoliang & He, Feng & Chen, Kaihua, 2019. "Exploring the effect of political borders on university-industry collaborative research performance: Evidence from China’s Guangdong province," Technovation, Elsevier, vol. 82, pages 58-69.
    4. Morescalchi, Andrea & Pammolli, Fabio & Penner, Orion & Petersen, Alexander M. & Riccaboni, Massimo, 2015. "The evolution of networks of innovators within and across borders: Evidence from patent data," Research Policy, Elsevier, vol. 44(3), pages 651-668.
    5. Montobbio, Fabio & Sterzi, Valerio, 2013. "The Globalization of Technology in Emerging Markets: A Gravity Model on the Determinants of International Patent Collaborations," World Development, Elsevier, vol. 44(C), pages 281-299.
    6. Luigi Aldieri & Gennaro Guida & Maxim Kotsemir & Concetto Paolo Vinci, 2019. "An investigation of impact of research collaboration on academic performance in Italy," Quality & Quantity: International Journal of Methodology, Springer, vol. 53(4), pages 2003-2040, July.
    7. Chengliang Liu & Caicheng Niu & Ji Han, 2019. "Spatial Dynamics of Intercity Technology Transfer Networks in China’s Three Urban Agglomerations: A Patent Transaction Perspective," Sustainability, MDPI, vol. 11(6), pages 1-24, March.
    8. Tatiana Plotnikova & Bastian Rake, 2014. "Collaboration in pharmaceutical research: exploration of country-level determinants," Scientometrics, Springer;Akadémiai Kiadó, vol. 98(2), pages 1173-1202, February.
    9. Sara Amoroso & Alex Coad & Nicola Grassano, 2017. "European R&D networks: A snapshot from the 7th EU Framework Programme," JRC Working Papers on Corporate R&D and Innovation JRC107546, Joint Research Centre (Seville site).
    10. Wang, Yunmin & Cao, Guohua & Yan, Youliang & Wang, Jingjing, 2022. "Does high-speed rail stimulate cross-city technological innovation collaboration? Evidence from China," Transport Policy, Elsevier, vol. 116(C), pages 119-131.
    11. Yindan Ye & Kevin De Moortel & Thomas Crispeels, 2020. "Network dynamics of Chinese university knowledge transfer," The Journal of Technology Transfer, Springer, vol. 45(4), pages 1228-1254, August.
    12. Xia Gao & Jiancheng Guan & Ronald Rousseau, 2011. "Mapping collaborative knowledge production in China using patent co-inventorships," Scientometrics, Springer;Akadémiai Kiadó, vol. 88(2), pages 343-362, August.
    13. Koen Frenken & Roderik Ponds & Frank Van Oort, 2010. "The citation impact of research collaboration in science‐based industries: A spatial‐institutional analysis," Papers in Regional Science, Wiley Blackwell, vol. 89(2), pages 351-271, June.
    14. Wentian Shi & Wenlong Yang & Debin Du, 2020. "The Scientific Cooperation Network of Chinese Scientists and Its Proximity Mechanism," Sustainability, MDPI, vol. 12(2), pages 1-18, January.
    15. Mafini Dosso & Antonio Vezzani, 2020. "Firm market valuation and intellectual property assets," Industry and Innovation, Taylor & Francis Journals, vol. 27(7), pages 705-729, August.
    16. Sara Amoroso & Alex Coad & Nicola Grassano, 2018. "European R&D networks: a snapshot from the 7th EU Framework Programme," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 27(5-6), pages 404-419, August.
    17. Mario Maggioni & Teodora Uberti & Mario Nosvelli, 2014. "Does intentional mean hierarchical? Knowledge flows and innovative performance of European regions," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 53(2), pages 453-485, September.
    18. Xie, Qijun & Su, Jun, 2021. "The spatial-temporal complexity and dynamics of research collaboration: Evidence from 297 cities in China (1985–2016)," Technological Forecasting and Social Change, Elsevier, vol. 162(C).
    19. Friedrich Dornbusch & Sidonia von Proff & Thomas Brenner, 2013. "The organizational and regional determinants of inter-regional collaborations – Academic inventors as bridging agents," Working Papers on Innovation and Space 2013-11, Philipps University Marburg, Department of Geography.
    20. Qin, Xionghe & Wang, Xueli & Kwan, Mei-Po, 2023. "The contrasting effects of interregional networks and local agglomeration on R&D productivity in Chinese provinces: Insights from an empirical spatial Durbin model," Technological Forecasting and Social Change, Elsevier, vol. 193(C).

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:scient:v:126:y:2021:i:3:d:10.1007_s11192-020-03828-4. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.