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Semiparametric analysis of multivariate panel count data with nonlinear interactions

Author

Listed:
  • Weiwei Wang

    (Zhejiang Gongshang University
    Zhejiang Gongshang University)

  • Yijun Wang

    (Zhejiang Gongshang University
    Zhejiang Gongshang University)

  • Xiaobing Zhao

    (Zhejiang University of Finance and Economics)

Abstract

Multivariate panel count data frequently arise in follow up studies involving several related types of recurrent events. For univariate panel count data, several varying coefficient models have been developed. However, varying coefficient models for multivariate panel count data remain to be studied. In this paper, we propose a varying coefficient mean model for multivariate panel count data to describe the possible nonlinear interact effects between the covariates and the local logarithm partial likelihood procedure is considered to estimate the unknown covariate effects. Furthermore, a Breslow-type estimator is constructed for the baseline mean functions. The consistency and asymptotic normality of the proposed estimators are established under some mild conditions. The utility of the proposed approach is evaluated by some numerical simulations and an application to a dataset of skin cancer study.

Suggested Citation

  • Weiwei Wang & Yijun Wang & Xiaobing Zhao, 2022. "Semiparametric analysis of multivariate panel count data with nonlinear interactions," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 28(1), pages 89-115, January.
  • Handle: RePEc:spr:lifeda:v:28:y:2022:i:1:d:10.1007_s10985-021-09537-1
    DOI: 10.1007/s10985-021-09537-1
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    References listed on IDEAS

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    1. Lu, Minggen & Zhang, Ying & Huang, Jian, 2009. "Semiparametric Estimation Methods for Panel Count Data Using Monotone B-Splines," Journal of the American Statistical Association, American Statistical Association, vol. 104(487), pages 1060-1070.
    2. X. Joan Hu & Jianguo Sun & Lee‐Jen Wei, 2003. "Regression Parameter Estimation from Panel Counts," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 30(1), pages 25-43, March.
    3. Li, Yang & He, Xin & Wang, Haiying & Zhang, Bin & Sun, Jianguo, 2015. "Semiparametric regression of multivariate panel count data with informative observation times," Journal of Multivariate Analysis, Elsevier, vol. 140(C), pages 209-219.
    4. Zhao, Xingqiu & Tong, Xingwei & Sun, Jianguo, 2013. "Robust estimation for panel count data with informative observation times," Computational Statistics & Data Analysis, Elsevier, vol. 57(1), pages 33-40.
    5. Xin He & Xuenan Feng & Xingwei Tong & Xingqiu Zhao, 2017. "Semiparametric partially linear varying coefficient models with panel count data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 23(3), pages 439-466, July.
    6. Huadong Zhao & Wanzhu Tu & Zhangsheng Yu, 2018. "A nonparametric time-varying coefficient model for panel count data," Journal of Nonparametric Statistics, Taylor & Francis Journals, vol. 30(3), pages 640-661, July.
    7. Zhang, Haixiang & Zhao, Hui & Sun, Jianguo & Wang, Dehui & Kim, KyungMann, 2013. "Regression analysis of multivariate panel count data with an informative observation process," Journal of Multivariate Analysis, Elsevier, vol. 119(C), pages 71-80.
    8. Zhao, Xingqiu & Tong, Xingwei, 2011. "Semiparametric regression analysis of panel count data with informative observation times," Computational Statistics & Data Analysis, Elsevier, vol. 55(1), pages 291-300, January.
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