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Technology sourcing and the dark side of open innovation: Evidence from the biopharmaceutical sector

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  • Purdy, Lauren
  • Eslami, Hadi
  • Eshghi, Kamran
  • Rod, Michel

Abstract

Firms in high-technology industries face a complex set of challenges to innovate successfully and continuously to gain a sustainable competitive advantage. Innovative new R&D project sourcing choices top this list of difficult and nuanced choices that firms must make in pursuit of innovation. Our research makes a significant and novel contribution to this interesting discourse and critically examines the sourcing decision (i.e., open vs. closed innovation) in the context of new product development in the biopharmaceutical sector. Specifically, we apply a project-level typology along the dimensions of new R&D project source and project familiarity. Drawing from transaction cost economics (TCE) and the knowledge-based view (KBV) theories, we empirically test our theoretically developed hypotheses on a dataset of 2,971 biopharmaceutical R&D projects spanning from 1985 to 2016. Results from our robust analysis show that both new R&D project source and project familiarity have significant direct effects on focal project performance outcomes (defined in this paper as likelihood of termination). We also determine that focal project familiarity has a significant moderating effect on the relationship between project source and performance outcome.

Suggested Citation

  • Purdy, Lauren & Eslami, Hadi & Eshghi, Kamran & Rod, Michel, 2023. "Technology sourcing and the dark side of open innovation: Evidence from the biopharmaceutical sector," Technovation, Elsevier, vol. 119(C).
  • Handle: RePEc:eee:techno:v:119:y:2023:i:c:s0166497222000682
    DOI: 10.1016/j.technovation.2022.102521
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    1. Joel A. C. Baum & Tony Calabrese & Brian S. Silverman, 2000. "Don't go it alone: alliance network composition and startups' performance in Canadian biotechnology," Strategic Management Journal, Wiley Blackwell, vol. 21(3), pages 267-294, March.
    2. David J. TEECE, 2008. "Profiting from technological innovation: Implications for integration, collaboration, licensing and public policy," World Scientific Book Chapters, in: The Transfer And Licensing Of Know-How And Intellectual Property Understanding the Multinational Enterprise in the Modern World, chapter 5, pages 67-87, World Scientific Publishing Co. Pte. Ltd..
    3. Foege, J. Nils & Lauritzen, Ghita Dragsdahl & Tietze, Frank & Salge, Torsten Oliver, 2019. "Reconceptualizing the paradox of openness: How solvers navigate sharing-protecting tensions in crowdsourcing," Research Policy, Elsevier, vol. 48(6), pages 1323-1339.
    4. Xie, Xuemei & Wang, Hongwei, 2020. "How can open innovation ecosystem modes push product innovation forward? An fsQCA analysis," Journal of Business Research, Elsevier, vol. 108(C), pages 29-41.
    5. Bronwyn H. Hall & Adam Jaffe & Manuel Trajtenberg, 2005. "Market Value and Patent Citations," RAND Journal of Economics, The RAND Corporation, vol. 36(1), pages 16-38, Spring.
    6. Cesaroni, Fabrizio, 2004. "Technological outsourcing and product diversification: do markets for technology affect firms' strategies?," Research Policy, Elsevier, vol. 33(10), pages 1547-1564, December.
    7. Hussinger, Katrin & Wastyn, Annelies, 2011. "In search for the not-invented-here syndrome: The role of knowledge sources and firm success," ZEW Discussion Papers 11-048, ZEW - Leibniz Centre for European Economic Research.
    8. Manpreet Hora & Dev K. Dutta, 2013. "Entrepreneurial Firms and Downstream Alliance Partnerships: Impact of Portfolio Depth and Scope on Technology Innovation and Commercialization Success," Production and Operations Management, Production and Operations Management Society, vol. 22(6), pages 1389-1400, November.
    9. Gautam Ahuja & Curba Morris Lampert, 2001. "Entrepreneurship in the large corporation: a longitudinal study of how established firms create breakthrough inventions," Strategic Management Journal, Wiley Blackwell, vol. 22(6‐7), pages 521-543, June.
    10. Sande, Jon Bingen & Ghosh, Mrinal, 2018. "Endogeneity in survey research," International Journal of Research in Marketing, Elsevier, vol. 35(2), pages 185-204.
    11. Luis Diestre & Nandini Rajagopalan, 2012. "Are all ‘sharks’ dangerous? new biotechnology ventures and partner selection in R&D alliances," Strategic Management Journal, Wiley Blackwell, vol. 33(10), pages 1115-1134, October.
    12. Alfred Osta & Bassem Maamari, 2020. "Openness in research and development: co-patenting impact on breakthrough innovations in the pharmaceutical industry," International Journal of Business Innovation and Research, Inderscience Enterprises Ltd, vol. 21(3), pages 395-408.
    13. Abhishek Borah & Gerard J. Tellis, 2014. "Make, Buy, or Ally? Choice of and Payoff from Announcements of Alternate Strategies for Innovations," Marketing Science, INFORMS, vol. 33(1), pages 114-133, January.
    14. Alex Coad & Paul Nightingale & Jack Stilgoe & Antonio Vezzani, 2021. "Editorial: the dark side of innovation," Industry and Innovation, Taylor & Francis Journals, vol. 28(1), pages 102-112, January.
    15. Jones, Gary K. & LanctotJR., Aldor & Teegen, Hildy J., 2001. "Determinants and performance impacts of external technology acquisition," Journal of Business Venturing, Elsevier, vol. 16(3), pages 255-283, May.
    16. Ebersberger, Bernd & Galia, Fabrice & Laursen, Keld & Salter, Ammon, 2021. "Inbound Open Innovation and Innovation Performance: A Robustness Study," Research Policy, Elsevier, vol. 50(7).
    17. Hervás-Oliver, José-Luis & Parrilli, Mario Davide & Rodríguez-Pose, Andrés & Sempere-Ripoll, Francisca, 2021. "The drivers of SME innovation in the regions of the EU," Research Policy, Elsevier, vol. 50(9).
    18. Lyu, Yibo & Zhu, Yuqing & Han, Shaojie & He, Binyuan & Bao, Lining, 2020. "Open innovation and innovation "Radicalness"—the moderating effect of network embeddedness," Technology in Society, Elsevier, vol. 62(C).
    19. Du, Jingshu & Leten, Bart & Vanhaverbeke, Wim, 2014. "Managing open innovation projects with science-based and market-based partners," Research Policy, Elsevier, vol. 43(5), pages 828-840.
    20. Thakur-Wernz, Pooja & Bruyaka, Olga & Contractor, Farok, 2020. "Antecedents and relative performance of sourcing choices for new product development projects," Technovation, Elsevier, vol. 90.
    21. Thomas Keil & Markku Maula & Henri Schildt & Shaker A. Zahra, 2008. "The effect of governance modes and relatedness of external business development activities on innovative performance," Strategic Management Journal, Wiley Blackwell, vol. 29(8), pages 895-907, August.
    22. Eungdo Kim & InGyu Lee & Hongbum Kim & Kwangsoo Shin, 2021. "Factors Affecting Outbound Open Innovation Performance in Bio-Pharmaceutical Industry-Focus on Out-Licensing Deals," Sustainability, MDPI, vol. 13(8), pages 1-17, April.
    23. Morgan, Todd & Obal, Michael & Jewell, Robert D., 2021. "Strategic change and innovation reputation: Opening up the innovation process," Journal of Business Research, Elsevier, vol. 132(C), pages 249-259.
    24. Seung Ho Park & Michael V. Russo, 1996. "When Competition Eclipses Cooperation: An Event History Analysis of Joint Venture Failure," Management Science, INFORMS, vol. 42(6), pages 875-890, June.
    25. Tzabbar, Daniel & Aharonson, Barak S. & Amburgey, Terry L., 2013. "When does tapping external sources of knowledge result in knowledge integration?," Research Policy, Elsevier, vol. 42(2), pages 481-494.
    26. Cabaleiro-Cerviño, Goretti & Burcharth, Ana, 2020. "Licensing agreements as signals of innovation: When do they impact market value?," Technovation, Elsevier, vol. 98(C).
    27. Hutton, Steven & Demir, Robert & Eldridge, Stephen, 2021. "How does open innovation contribute to the firm's dynamic capabilities?," Technovation, Elsevier, vol. 106(C).
    28. Carayannopoulos, Sofy & Auster, Ellen R., 2010. "External knowledge sourcing in biotechnology through acquisition versus alliance: A KBV approach," Research Policy, Elsevier, vol. 39(2), pages 254-267, March.
    29. Berchicci, Luca, 2013. "Towards an open R&D system: Internal R&D investment, external knowledge acquisition and innovative performance," Research Policy, Elsevier, vol. 42(1), pages 117-127.
    30. Bruno Cassiman & Reinhilde Veugelers, 2006. "In Search of Complementarity in Innovation Strategy: Internal R& D and External Knowledge Acquisition," Management Science, INFORMS, vol. 52(1), pages 68-82, January.
    31. Nishimura, Junichi & Okada, Yosuke, 2014. "R&D portfolios and pharmaceutical licensing," Research Policy, Elsevier, vol. 43(7), pages 1250-1263.
    32. Stefan, Ioana & Hurmelinna-Laukkanen, Pia & Vanhaverbeke, Wim & Oikarinen, Eeva-Liisa, 2022. "The dark side of open innovation: Individual affective responses as hidden tolls of the paradox of openness," Journal of Business Research, Elsevier, vol. 138(C), pages 360-373.
    33. Ha Hoang & Frank T. Rothaermel, 2010. "Leveraging internal and external experience: exploration, exploitation, and R&D project performance," Strategic Management Journal, Wiley Blackwell, vol. 31(7), pages 734-758, July.
    34. Lo Nigro, Giovanna & Morreale, Azzurra & Enea, Gianluca, 2014. "Open innovation: A real option to restore value to the biopharmaceutical R&D," International Journal of Production Economics, Elsevier, vol. 149(C), pages 183-193.
    35. Rothaermel, Frank T. & Deeds, David L., 2006. "Alliance type, alliance experience and alliance management capability in high-technology ventures," Journal of Business Venturing, Elsevier, vol. 21(4), pages 429-460, July.
    36. Frank T. Rothaermel & Maria Tereza Alexandre, 2009. "Ambidexterity in Technology Sourcing: The Moderating Role of Absorptive Capacity," Organization Science, INFORMS, vol. 20(4), pages 759-780, August.
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