IDEAS home Printed from https://ideas.repec.org/a/eee/reensy/v213y2021ics0951832021002040.html
   My bibliography  Save this article

Sensitivity analysis study on the effect of the fluid mechanics assumptions for the computation of electrical conductivity of flowing human blood

Author

Listed:
  • Melito, Gian Marco
  • Müller, Thomas Stephan
  • Badeli, Vahid
  • Ellermann, Katrin
  • Brenn, Günter
  • Reinbacher-Köstinger, Alice

Abstract

Impedance cardiography is a non-invasive methodology for measuring cardiodynamic parameters, such as stroke volume and heart rate, as well as cardiac output. For the measurement, the electric conductivity of blood is important. The conductivity of blood depends on various parameters, such as the haematocrit value as well as the red blood cells’ (RBC) shape and orientation. In models, the response is usually affected by uncertainty, which may lead to inaccurate medical diagnosis. Therefore, a ranking of the influence of the model’s input factors may be necessary. Also, physically and physiologically correct assumptions are fundamental for the accuracy of the model. The basis for predicting the conductivity of blood in this study is the Maxwell–Fricke theory, which allows computing the electrical bulk conductivity of quiescent blood. For flowing blood, fluid mechanics has to be coupled in the modelling phase.

Suggested Citation

  • Melito, Gian Marco & Müller, Thomas Stephan & Badeli, Vahid & Ellermann, Katrin & Brenn, Günter & Reinbacher-Köstinger, Alice, 2021. "Sensitivity analysis study on the effect of the fluid mechanics assumptions for the computation of electrical conductivity of flowing human blood," Reliability Engineering and System Safety, Elsevier, vol. 213(C).
    • Handle: RePEc:eee:reensy:v:213:y:2021:i:c:s0951832021002040
    DOI: 10.1016/j.ress.2021.107663
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0951832021002040
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.ress.2021.107663?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Saltelli, Andrea & Ratto, Marco & Tarantola, Stefano & Campolongo, Francesca, 2006. "Sensitivity analysis practices: Strategies for model-based inference," Reliability Engineering and System Safety, Elsevier, vol. 91(10), pages 1109-1125.
    2. Sudret, Bruno, 2008. "Global sensitivity analysis using polynomial chaos expansions," Reliability Engineering and System Safety, Elsevier, vol. 93(7), pages 964-979.
    3. Crestaux, Thierry & Le Maıˆtre, Olivier & Martinez, Jean-Marc, 2009. "Polynomial chaos expansion for sensitivity analysis," Reliability Engineering and System Safety, Elsevier, vol. 94(7), pages 1161-1172.
    4. Borgonovo, E., 2007. "A new uncertainty importance measure," Reliability Engineering and System Safety, Elsevier, vol. 92(6), pages 771-784.
    5. Borgonovo, E. & Peccati, L., 2004. "Sensitivity analysis in investment project evaluation," International Journal of Production Economics, Elsevier, vol. 90(1), pages 17-25, July.
    6. Borgonovo, Emanuele & Plischke, Elmar, 2016. "Sensitivity analysis: A review of recent advances," European Journal of Operational Research, Elsevier, vol. 248(3), pages 869-887.
    7. Jeremy E. Oakley & Anthony O'Hagan, 2004. "Probabilistic sensitivity analysis of complex models: a Bayesian approach," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 66(3), pages 751-769, August.
    8. M. Saisana & A. Saltelli & S. Tarantola, 2005. "Uncertainty and sensitivity analysis techniques as tools for the quality assessment of composite indicators," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 168(2), pages 307-323, March.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Wang, Zhenqiang & Jia, Gaofeng, 2023. "Extended sample-based approach for efficient sensitivity analysis of group of random variables," Reliability Engineering and System Safety, Elsevier, vol. 231(C).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Mirko Ginocchi & Ferdinanda Ponci & Antonello Monti, 2021. "Sensitivity Analysis and Power Systems: Can We Bridge the Gap? A Review and a Guide to Getting Started," Energies, MDPI, vol. 14(24), pages 1-59, December.
    2. Borgonovo, Emanuele & Plischke, Elmar, 2016. "Sensitivity analysis: A review of recent advances," European Journal of Operational Research, Elsevier, vol. 248(3), pages 869-887.
    3. Plischke, Elmar & Borgonovo, Emanuele & Smith, Curtis L., 2013. "Global sensitivity measures from given data," European Journal of Operational Research, Elsevier, vol. 226(3), pages 536-550.
    4. Wu, Zeping & Wang, Wenjie & Wang, Donghui & Zhao, Kun & Zhang, Weihua, 2019. "Global sensitivity analysis using orthogonal augmented radial basis function," Reliability Engineering and System Safety, Elsevier, vol. 185(C), pages 291-302.
    5. Konakli, Katerina & Sudret, Bruno, 2016. "Global sensitivity analysis using low-rank tensor approximations," Reliability Engineering and System Safety, Elsevier, vol. 156(C), pages 64-83.
    6. Xie, Xiangzhong & Schenkendorf, René & Krewer, Ulrike, 2019. "Efficient sensitivity analysis and interpretation of parameter correlations in chemical engineering," Reliability Engineering and System Safety, Elsevier, vol. 187(C), pages 159-173.
    7. Shang, Xiaobing & Su, Li & Fang, Hai & Zeng, Bowen & Zhang, Zhi, 2023. "An efficient multi-fidelity Kriging surrogate model-based method for global sensitivity analysis," Reliability Engineering and System Safety, Elsevier, vol. 229(C).
    8. Puppo, L. & Pedroni, N. & Maio, F. Di & Bersano, A. & Bertani, C. & Zio, E., 2021. "A Framework based on Finite Mixture Models and Adaptive Kriging for Characterizing Non-Smooth and Multimodal Failure Regions in a Nuclear Passive Safety System," Reliability Engineering and System Safety, Elsevier, vol. 216(C).
    9. Pesenti, Silvana M. & Millossovich, Pietro & Tsanakas, Andreas, 2019. "Reverse sensitivity testing: What does it take to break the model?," European Journal of Operational Research, Elsevier, vol. 274(2), pages 654-670.
    10. Lambert, Romain S.C. & Lemke, Frank & Kucherenko, Sergei S. & Song, Shufang & Shah, Nilay, 2016. "Global sensitivity analysis using sparse high dimensional model representations generated by the group method of data handling," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 128(C), pages 42-54.
    11. Turati, Pietro & Pedroni, Nicola & Zio, Enrico, 2017. "Simulation-based exploration of high-dimensional system models for identifying unexpected events," Reliability Engineering and System Safety, Elsevier, vol. 165(C), pages 317-330.
    12. Yun, Wanying & Lu, Zhenzhou & Jiang, Xian, 2019. "An efficient method for moment-independent global sensitivity analysis by dimensional reduction technique and principle of maximum entropy," Reliability Engineering and System Safety, Elsevier, vol. 187(C), pages 174-182.
    13. Emanuele Borgonovo & Gordon B. Hazen & Elmar Plischke, 2016. "A Common Rationale for Global Sensitivity Measures and Their Estimation," Risk Analysis, John Wiley & Sons, vol. 36(10), pages 1871-1895, October.
    14. Chen, Xin & Molina-Cristóbal, Arturo & Guenov, Marin D. & Riaz, Atif, 2019. "Efficient method for variance-based sensitivity analysis," Reliability Engineering and System Safety, Elsevier, vol. 181(C), pages 97-115.
    15. Emanuele Borgonovo & William Castaings & Stefano Tarantola, 2011. "Moment Independent Importance Measures: New Results and Analytical Test Cases," Risk Analysis, John Wiley & Sons, vol. 31(3), pages 404-428, March.
    16. Wu, Zeping & Wang, Donghui & Okolo N, Patrick & Hu, Fan & Zhang, Weihua, 2016. "Global sensitivity analysis using a Gaussian Radial Basis Function metamodel," Reliability Engineering and System Safety, Elsevier, vol. 154(C), pages 171-179.
    17. Mara, Thierry A. & Tarantola, Stefano, 2012. "Variance-based sensitivity indices for models with dependent inputs," Reliability Engineering and System Safety, Elsevier, vol. 107(C), pages 115-121.
    18. Ehre, Max & Papaioannou, Iason & Straub, Daniel, 2020. "Global sensitivity analysis in high dimensions with PLS-PCE," Reliability Engineering and System Safety, Elsevier, vol. 198(C).
    19. Soha Saad & Florence Ossart & Jean Bigeon & Etienne Sourdille & Harold Gance, 2021. "Global Sensitivity Analysis Applied to Train Traffic Rescheduling: A Comparative Study," Energies, MDPI, vol. 14(19), pages 1-29, October.
    20. Xiang Peng & Xiaoqing Xu & Jiquan Li & Shaofei Jiang, 2021. "A Sampling-Based Sensitivity Analysis Method Considering the Uncertainties of Input Variables and Their Distribution Parameters," Mathematics, MDPI, vol. 9(10), pages 1-18, May.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:reensy:v:213:y:2021:i:c:s0951832021002040. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: https://www.journals.elsevier.com/reliability-engineering-and-system-safety .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.