IDEAS home Printed from https://ideas.repec.org/a/eee/ehbiol/v47y2022ics1570677x2200051x.html
   My bibliography  Save this article

Heterogeneity in disease resistance and the impact of antibiotics in the US

Author

Listed:
  • Cook, C. Justin
  • Fletcher, Jason M.

Abstract

We hypothesize that the impact of antibiotics is moderated by a population’s inherent (genetic) resistance to infectious disease. Using the introduction of sulfa drugs in 1937, we show that US states that are more genetically susceptible to infectious disease saw larger declines in their bacterial mortality rates following the introduction of sulfa drugs in 1937. This suggests area-level genetic endowments of disease resistance and the discovery of medical technologies have acted as substitutes in determining levels of health across the US. We also document immediate effects of sulfa drug exposure to the age of the workforce and cumulative effects on educational attainment for cohorts exposed to sulfa drugs in early life.

Suggested Citation

  • Cook, C. Justin & Fletcher, Jason M., 2022. "Heterogeneity in disease resistance and the impact of antibiotics in the US," Economics & Human Biology, Elsevier, vol. 47(C).
    • Handle: RePEc:eee:ehbiol:v:47:y:2022:i:c:s1570677x2200051x
    DOI: 10.1016/j.ehb.2022.101155
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S1570677X2200051X
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.ehb.2022.101155?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to look for a different version below or search for a different version of it.

    Other versions of this item:

    References listed on IDEAS

    as
    1. Hansen, Casper Worm, 2014. "Cause of death and development in the US," Journal of Development Economics, Elsevier, vol. 109(C), pages 143-153.
    2. Adriana Lleras-Muney, 2005. "The Relationship Between Education and Adult Mortality in the United States," The Review of Economic Studies, Review of Economic Studies Ltd, vol. 72(1), pages 189-221.
    3. Seema Jayachandran & Adriana Lleras-Muney & Kimberly V. Smith, 2010. "Modern Medicine and the Twentieth Century Decline in Mortality: Evidence on the Impact of Sulfa Drugs," American Economic Journal: Applied Economics, American Economic Association, vol. 2(2), pages 118-146, April.
    4. Lleras-Muney, Adriana, 2002. "Were Compulsory Attendance and Child Labor Laws Effective? An Analysis from 1915 to 1939," Journal of Law and Economics, University of Chicago Press, vol. 45(2), pages 401-435, October.
    5. David Cutler & Grant Miller, 2005. "The role of public health improvements in health advances: The twentieth-century United States," Demography, Springer;Population Association of America (PAA), vol. 42(1), pages 1-22, February.
    6. Chad Turner & Robert Tamura & Sean Mulholland & Scott Baier, 2007. "Education and income of the states of the United States: 1840–2000," Journal of Economic Growth, Springer, vol. 12(2), pages 101-158, June.
    7. C. Justin Cook, 2015. "The Natural Selection of Infectious Disease Resistance and Its Effect on Contemporary Health," The Review of Economics and Statistics, MIT Press, vol. 97(4), pages 742-757, October.
    8. Ideen A Riahi, 2021. "Animals and the prehistoric origins of economic development [The colonial origins of comparative development: an empirical investigation]," European Review of Economic History, European Historical Economics Society, vol. 25(2), pages 247-279.
    9. Daron Acemoglu & Simon Johnson, 2007. "Disease and Development: The Effect of Life Expectancy on Economic Growth," Journal of Political Economy, University of Chicago Press, vol. 115(6), pages 925-985, December.
    10. Nathan D. Wolfe & Claire Panosian Dunavan & Jared Diamond, 2007. "Origins of major human infectious diseases," Nature, Nature, vol. 447(7142), pages 279-283, May.
    11. Riahi, Ideen, 2017. "Colonialism and genetics of comparative development," Economics & Human Biology, Elsevier, vol. 27(PA), pages 55-73.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Hansen, Casper Worm, 2014. "Cause of death and development in the US," Journal of Development Economics, Elsevier, vol. 109(C), pages 143-153.
    2. Juliana Jaramillo-Echeverri & Adolfo Meisel-Roca & María Teresa Ramírez-Giraldo, 2019. "More than 100 years of improvements in living standards: the case of Colombia," Cliometrica, Springer;Cliometric Society (Association Francaise de Cliométrie), vol. 13(3), pages 323-366, September.
    3. Mariko J. Klasing & Petros Milionis, 2020. "The international epidemiological transition and the education gender gap," Journal of Economic Growth, Springer, vol. 25(1), pages 37-86, March.
    4. Kotschy, Rainer, 2021. "Health dynamics shape life-cycle incomes," Journal of Health Economics, Elsevier, vol. 75(C).
    5. Alex Hollingsworth & Krzysztof Karbownik & Melissa A. Thomasson & Anthony Wray, 2022. "The Gift of a Lifetime: The Hospital, Modern Medicine, and Mortality," NBER Working Papers 30663, National Bureau of Economic Research, Inc.
    6. Leandro Prados de la Escosura, 2021. "Augmented human development in the age of globalization," Economic History Review, Economic History Society, vol. 74(4), pages 946-975, November.
    7. Casper Worm Hansen & Holger Strulik, 2017. "Life expectancy and education: evidence from the cardiovascular revolution," Journal of Economic Growth, Springer, vol. 22(4), pages 421-450, December.
    8. Adolfo Meisel-Roca & Juliana Jaramillo-Echeverri & María Teresa Ramírez-Giraldo, 2018. "Más de cien años de avances en el nivel de vida: El caso de Colombia," Cuadernos de Historia Económica 46, Banco de la Republica de Colombia.
    9. David Cutler & Angus Deaton & Adriana Lleras-Muney, 2006. "The Determinants of Mortality," Journal of Economic Perspectives, American Economic Association, vol. 20(3), pages 97-120, Summer.
    10. Leandro Prados de la Escosura, 2015. "World Human Development: 1870–2007," Review of Income and Wealth, International Association for Research in Income and Wealth, vol. 61(2), pages 220-247, June.
    11. Hoehn-Velasco, Lauren, 2018. "Explaining declines in US rural mortality, 1910–1933: The role of county health departments," Explorations in Economic History, Elsevier, vol. 70(C), pages 42-72.
    12. Casper Worm Hansen, 2012. "Causes of mortality and development: Evidence from large health shocks in 20th century America," Economics Working Papers 2012-29, Department of Economics and Business Economics, Aarhus University.
    13. Dora L. Costa, 2015. "Health and the Economy in the United States from 1750 to the Present," Journal of Economic Literature, American Economic Association, vol. 53(3), pages 503-570, September.
    14. Jack, William & Lewis, Maureen, 2009. "Health investments and economic growth : macroeconomic evidence and microeconomic foundations," Policy Research Working Paper Series 4877, The World Bank.
    15. Titus J. Galama & Hans van Kippersluis, 2015. "A Theory of Education and Health," CINCH Working Paper Series 1503, Universitaet Duisburg-Essen, Competent in Competition and Health, revised Mar 2015.
    16. David Canning, 2012. "Progress in Health around the World," Journal of Development Studies, Taylor & Francis Journals, vol. 48(12), pages 1784-1798, December.
    17. Lleras-Muney, Adriana & Price, Joseph & Yue, Dahai, 2022. "The association between educational attainment and longevity using individual-level data from the 1940 census," Journal of Health Economics, Elsevier, vol. 84(C).
    18. Katherine Eriksson & Gregory T. Niemesh & Melissa Thomasson, 2017. "Revising Infant Mortality Rates for the Early 20th Century United States," NBER Working Papers 23263, National Bureau of Economic Research, Inc.
    19. Adriana Lleras-Muney & Joseph Price & Dahai Yue, 2020. "The Association Between Educational Attainment and Longevity using Individual Level Data from the 1940 Census," NBER Working Papers 27514, National Bureau of Economic Research, Inc.
    20. Prados de la Escosura, Leandro, 2023. "Health, income, and the preston curve: A long view," Economics & Human Biology, Elsevier, vol. 48(C).

    More about this item

    Keywords

    Difference-in-differences; Human Capital; Infectious disease; Genetic Resistance; Genetic Diversity; Antibiotics;
    All these keywords.

    JEL classification:

    • I1 - Health, Education, and Welfare - - Health
    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality
    • I15 - Health, Education, and Welfare - - Health - - - Health and Economic Development
    • J1 - Labor and Demographic Economics - - Demographic Economics

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:ehbiol:v:47:y:2022:i:c:s1570677x2200051x. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/inca/622964 .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.