IDEAS home Printed from https://ideas.repec.org/a/eee/csdana/v144y2020ics0167947319302294.html
   My bibliography  Save this article

Semiparametric estimation for the non-mixture cure model in case-cohort and nested case-control studies

Author

Listed:
  • Han, Bo
  • Wang, Xiaoguang

Abstract

Case-cohort and nested case-control designs are widely used strategies to reduce costs of covariate measurements in epidemiological cohort studies. A unified likelihood framework for two cohort designs is constructed and two statistical procedures are presented for making inference about the effects of incomplete covariates on the cumulative incidence of clinical event time. A pseudo-maximum likelihood estimation based on the sieve method is developed for the semiparametric non-mixture cure model, which can handle missing covariates and a cure fraction occurring in censored survival data. The resulting estimators are shown to be consistent and asymptotically normal in both case-cohort and nested case-control studies. In addition, for two cohort designs, an expectation–maximization (EM) algorithm is developed to simplify the maximization of the likelihood function with the Bernstein-based smoothing technique. Such a procedure would allow one to estimate the nonparametric component of the semiparametric model in closed form and relieve the computational burden. Simulation studies demonstrate that the proposed estimators have good properties in practical situations, and a motivating application to real data is provided to illustrate the methodology.

Suggested Citation

  • Han, Bo & Wang, Xiaoguang, 2020. "Semiparametric estimation for the non-mixture cure model in case-cohort and nested case-control studies," Computational Statistics & Data Analysis, Elsevier, vol. 144(C).
    • Handle: RePEc:eee:csdana:v:144:y:2020:i:c:s0167947319302294
    DOI: 10.1016/j.csda.2019.106874
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167947319302294
    Download Restriction: Full text for ScienceDirect subscribers only.
    File URL: https://libkey.io/10.1016/j.csda.2019.106874?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Suhyun Kang & Wenbin Lu & Mengling Liu, 2017. "Efficient estimation for accelerated failure time model under case-cohort and nested case-control sampling," Biometrics, The International Biometric Society, vol. 73(1), pages 114-123, March.
    2. Wenbin Lu & Anastasios A. Tsiatis, 2006. "Semiparametric transformation models for the case-cohort study," Biometrika, Biometrika Trust, vol. 93(1), pages 207-214, March.
    3. Lan Kong & Jianwen Cai, 2009. "Case–Cohort Analysis with Accelerated Failure Time Model," Biometrics, The International Biometric Society, vol. 65(1), pages 135-142, March.
    4. Norman E. Breslow & Jon A. Wellner, 2007. "Weighted Likelihood for Semiparametric Models and Two‐phase Stratified Samples, with Application to Cox Regression," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 34(1), pages 86-102, March.
    5. Hu, Tao & Xiang, Liming, 2013. "Efficient estimation for semiparametric cure models with interval-censored data," Journal of Multivariate Analysis, Elsevier, vol. 121(C), pages 139-151.
    6. Liu, Hao & Shen, Yu, 2009. "A Semiparametric Regression Cure Model for Interval-Censored Data," Journal of the American Statistical Association, American Statistical Association, vol. 104(487), pages 1168-1178.
    7. Hu, Tao & Xiang, Liming, 2016. "Partially linear transformation cure models for interval-censored data," Computational Statistics & Data Analysis, Elsevier, vol. 93(C), pages 257-269.
    8. Bertrand, Aurelie & Legrand, Catherine & Leonard, Daniel & Van Keilegom, Ingrid, 2017. "Robustness of estimation methods in a survival cure model with mismeasured covariates," LIDAM Reprints ISBA 2017021, Université catholique de Louvain, Institute of Statistics, Biostatistics and Actuarial Sciences (ISBA).
    9. Yun Chen H., 2001. "Weighted Semiparametric Likelihood Method for Fitting a Proportional Odds Regression Model to Data From the Case-Cohort Design," Journal of the American Statistical Association, American Statistical Association, vol. 96, pages 1446-1457, December.
    10. Carvalho Lopes, Celia Mendes & Bolfarine, Heleno, 2012. "Random effects in promotion time cure rate models," Computational Statistics & Data Analysis, Elsevier, vol. 56(1), pages 75-87, January.
    11. Peng, Yingwei, 2003. "Fitting semiparametric cure models," Computational Statistics & Data Analysis, Elsevier, vol. 41(3-4), pages 481-490, January.
    12. Thomas H. Scheike & Torben Martinussen, 2004. "Maximum Likelihood Estimation for Cox's Regression Model Under Case–Cohort Sampling," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 31(2), pages 283-293, June.
    13. Donglin Zeng & D. Y. Lin, 2014. "Efficient Estimation of Semiparametric Transformation Models for Two-Phase Cohort Studies," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 109(505), pages 371-383, March.
    14. Yu, Binbing & Peng, Yingwei, 2008. "Mixture cure models for multivariate survival data," Computational Statistics & Data Analysis, Elsevier, vol. 52(3), pages 1524-1532, January.
    15. Bertrand, A. & Legrand, C. & Léonard, D. & Van Keilegom, I., 2017. "Robustness of estimation methods in a survival cure model with mismeasured covariates," Computational Statistics & Data Analysis, Elsevier, vol. 113(C), pages 3-18.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Qingning Zhou & Jianwen Cai & Haibo Zhou, 2018. "Outcome†dependent sampling with interval†censored failure time data," Biometrics, The International Biometric Society, vol. 74(1), pages 58-67, March.
    2. Xiaoguang Wang & Ziwen Wang, 2021. "EM algorithm for the additive risk mixture cure model with interval-censored data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 27(1), pages 91-130, January.
    3. Suhyun Kang & Wenbin Lu & Mengling Liu, 2017. "Efficient estimation for accelerated failure time model under case-cohort and nested case-control sampling," Biometrics, The International Biometric Society, vol. 73(1), pages 114-123, March.
    4. Mingzhe Wu & Ming Zheng & Wen Yu & Ruofan Wu, 2018. "Estimation and variable selection for semiparametric transformation models under a more efficient cohort sampling design," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 27(3), pages 570-596, September.
    5. Hu, Tao & Xiang, Liming, 2016. "Partially linear transformation cure models for interval-censored data," Computational Statistics & Data Analysis, Elsevier, vol. 93(C), pages 257-269.
    6. Li, Shuwei & Hu, Tao & Zhao, Xingqiu & Sun, Jianguo, 2019. "A class of semiparametric transformation cure models for interval-censored failure time data," Computational Statistics & Data Analysis, Elsevier, vol. 133(C), pages 153-165.
    7. Zheng, Ming & Zhao, Ziqiang & Yu, Wen, 2013. "Quantile regression analysis of case-cohort data," Journal of Multivariate Analysis, Elsevier, vol. 122(C), pages 20-34.
    8. Jing Zhang & Haibo Zhou & Yanyan Liu & Jianwen Cai, 2021. "Feature screening for case‐cohort studies with failure time outcome," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 48(1), pages 349-370, March.
    9. Jieli Ding & Tsui-Shan Lu & Jianwen Cai & Haibo Zhou, 2017. "Recent progresses in outcome-dependent sampling with failure time data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 23(1), pages 57-82, January.
    10. Yuan Wu & Christina D. Chambers & Ronghui Xu, 2019. "Semiparametric sieve maximum likelihood estimation under cure model with partly interval censored and left truncated data for application to spontaneous abortion," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 25(3), pages 507-528, July.
    11. Ying Yan & Haibo Zhou & Jianwen Cai, 2017. "Improving efficiency of parameter estimation in case-cohort studies with multivariate failure time data," Biometrics, The International Biometric Society, vol. 73(3), pages 1042-1052, September.
    12. Liu, Xiaoyu & Xiang, Liming, 2021. "Generalized accelerated hazards mixture cure models with interval-censored data," Computational Statistics & Data Analysis, Elsevier, vol. 161(C).
    13. Shuying Wang & Chunjie Wang & Jianguo Sun, 2021. "An additive hazards cure model with informative interval censoring," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 27(2), pages 244-268, April.
    14. Xu, Yang & Zhao, Shishun & Hu, Tao & Sun, Jianguo, 2021. "Variable selection for generalized odds rate mixture cure models with interval-censored failure time data," Computational Statistics & Data Analysis, Elsevier, vol. 156(C).
    15. Li, Mengyan & Ma, Yanyuan & Li, Runze, 2019. "Semiparametric regression for measurement error model with heteroscedastic error," Journal of Multivariate Analysis, Elsevier, vol. 171(C), pages 320-338.
    16. Chen, Chyong-Mei & Lu, Tai-Fang C., 2012. "Marginal analysis of multivariate failure time data with a surviving fraction based on semiparametric transformation cure models," Computational Statistics & Data Analysis, Elsevier, vol. 56(3), pages 645-655.
    17. Jon Arni Steingrimsson & Robert L. Strawderman, 2017. "Estimation in the Semiparametric Accelerated Failure Time Model With Missing Covariates: Improving Efficiency Through Augmentation," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 112(519), pages 1221-1235, July.
    18. J. F. Lawless, 2018. "Two-phase outcome-dependent studies for failure times and testing for effects of expensive covariates," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 24(1), pages 28-44, January.
    19. Yanqing Sun & Xiyuan Qian & Qiong Shou & Peter B. Gilbert, 2017. "Analysis of two-phase sampling data with semiparametric additive hazards models," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 23(3), pages 377-399, July.
    20. Hu, Tao & Xiang, Liming, 2013. "Efficient estimation for semiparametric cure models with interval-censored data," Journal of Multivariate Analysis, Elsevier, vol. 121(C), pages 139-151.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:144:y:2020:i:c:s0167947319302294. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/csda .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.