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Variable selection for generalized odds rate mixture cure models with interval-censored failure time data

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  • Xu, Yang
  • Zhao, Shishun
  • Hu, Tao
  • Sun, Jianguo

Abstract

Variable selection for failure time data with a cured fraction has been discussed by many authors but most of existing methods apply only to right-censored failure time data. In this paper, we consider variable selection when one faces interval-censored failure time data arising from a general class of generalized odds rate mixture cure models, and we propose a penalized variable selection method by maximizing a derived penalized likelihood function. In the method, the sieve approach is employed to approximate the unknown function, and it is implemented using a novel penalized expectation–maximization (EM) algorithm. Also the asymptotic properties of the proposed estimators of regression parameters, including the oracle property, are obtained. Furthermore, a simulation study is conducted to assess the finite sample performance of the proposed method, and the results indicate that it works well in practice. Finally, the approach is applied to a set of real data on childhood mortality taken from the Nigeria Demographic and Health Survey.

Suggested Citation

  • Xu, Yang & Zhao, Shishun & Hu, Tao & Sun, Jianguo, 2021. "Variable selection for generalized odds rate mixture cure models with interval-censored failure time data," Computational Statistics & Data Analysis, Elsevier, vol. 156(C).
    • Handle: RePEc:eee:csdana:v:156:y:2021:i:c:s0167947320302061
    DOI: 10.1016/j.csda.2020.107115
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    References listed on IDEAS

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