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Personalized Chronic Disease Follow‐Up Appointments: Risk‐Stratified Care Through Big Data

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  • Zlatana Nenova
  • Jennifer Shang

Abstract

Managing patients with chronic conditions is challenging. It requires timely care adjustments based on the patient's health status. We leverage big data to optimize patient monitoring frequencies and improve treatment. Our research is motivated by the need to improve patient care at the Veterans Affairs (VA) hospitals. We propose an integrated model to better serve patients with chronic kidney disease (CKD). CKD is prevalent, complex, and costly. The demand for kidney care has steadily increased; however, there is a decline in the availability of nephrologists. We propose a finite‐horizon Markov decision process (MDP) model, which utilizes evidence‐based and data‐driven approach to identify the best follow‐up appointment schedule for patients. The MDP model helps attain an optimal dynamic treatment plan to enhance patient's quality of life. It is parameterized by data from 11 US Department of Veterans Affairs hospitals, containing 68,513 CKD patients (mostly males between 60 and 90 years old) geographically dispersed throughout the United States between January 1, 2009 and February 21, 2016. Through various estimates and assumptions, we propose an optimal monitoring policy. We find that CKD severity, comorbidities, age, and distance to nephrologist all play roles in shaping patients’ needs of care. Through the VA clinical data, we have numerically validated our recommendation and shown that it considerably outperforms the current kidney care guidelines adopted by the VA.

Suggested Citation

  • Zlatana Nenova & Jennifer Shang, 2022. "Personalized Chronic Disease Follow‐Up Appointments: Risk‐Stratified Care Through Big Data," Production and Operations Management, Production and Operations Management Society, vol. 31(2), pages 583-606, February.
  • Handle: RePEc:bla:popmgt:v:31:y:2022:i:2:p:583-606
    DOI: 10.1111/poms.13568
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    1. Patrick W. Sullivan & Vahram Ghushchyan, 2006. "Preference-Based EQ-5D Index Scores for Chronic Conditions in the United States," Medical Decision Making, , vol. 26(4), pages 410-420, July.
    2. Jingyu Zhang & Brian T. Denton & Hari Balasubramanian & Nilay D. Shah & Brant A. Inman, 2012. "Optimization of Prostate Biopsy Referral Decisions," Manufacturing & Service Operations Management, INFORMS, vol. 14(4), pages 529-547, October.
    3. Turgay Ayer & Oguzhan Alagoz & Natasha K. Stout, 2012. "OR Forum---A POMDP Approach to Personalize Mammography Screening Decisions," Operations Research, INFORMS, vol. 60(5), pages 1019-1034, October.
    4. Brent Moritz & Enno Siemsen & Mirko Kremer, 2014. "Judgmental Forecasting: Cognitive Reflection and Decision Speed," Production and Operations Management, Production and Operations Management Society, vol. 23(7), pages 1146-1160, July.
    5. Oguzhan Alagoz & Cindy L. Bryce & Steven Shechter & Andrew Schaefer & Chung-Chou H. Chang & Derek C. Angus & Mark S. Roberts, 2005. "Incorporating Biological Natural History in Simulation Models: Empirical Estimates of the Progression of End-Stage Liver Disease," Medical Decision Making, , vol. 25(6), pages 620-632, November.
    6. Steven M. Shechter & Matthew D. Bailey & Andrew J. Schaefer & Mark S. Roberts, 2008. "The Optimal Time to Initiate HIV Therapy Under Ordered Health States," Operations Research, INFORMS, vol. 56(1), pages 20-33, February.
    7. Seetharaman, P B & Chintagunta, Pradeep K, 2003. "The Proportional Hazard Model for Purchase Timing: A Comparison of Alternative Specifications," Journal of Business & Economic Statistics, American Statistical Association, vol. 21(3), pages 368-382, July.
    8. Jonathan Patrick & Martin L. Puterman & Maurice Queyranne, 2008. "Dynamic Multipriority Patient Scheduling for a Diagnostic Resource," Operations Research, INFORMS, vol. 56(6), pages 1507-1525, December.
    9. Jonathan E. Helm & Mariel S. Lavieri & Mark P. Van Oyen & Joshua D. Stein & David C. Musch, 2015. "Dynamic Forecasting and Control Algorithms of Glaucoma Progression for Clinician Decision Support," Operations Research, INFORMS, vol. 63(5), pages 979-999, October.
    10. Jacob Feldman & Nan Liu & Huseyin Topaloglu & Serhan Ziya, 2014. "Appointment Scheduling Under Patient Preference and No-Show Behavior," Operations Research, INFORMS, vol. 62(4), pages 794-811, August.
    11. Claude Lefévre, 1981. "Optimal Control of a Birth and Death Epidemic Process," Operations Research, INFORMS, vol. 29(5), pages 971-982, October.
    12. Xiaodan Zhu & Anh Ninh & Hui Zhao & Zhenming Liu, 2021. "Demand Forecasting with Supply‐Chain Information and Machine Learning: Evidence in the Pharmaceutical Industry," Production and Operations Management, Production and Operations Management Society, vol. 30(9), pages 3231-3252, September.
    13. Robin M. Hogarth & Spyros Makridakis, 1981. "Forecasting and Planning: An Evaluation," Management Science, INFORMS, vol. 27(2), pages 115-138, February.
    14. Lauren N. Steimle & Brian T. Denton, 2017. "Markov Decision Processes for Screening and Treatment of Chronic Diseases," International Series in Operations Research & Management Science, in: Richard J. Boucherie & Nico M. van Dijk (ed.), Markov Decision Processes in Practice, chapter 0, pages 189-222, Springer.
    15. Diwakar Gupta & Lei Wang, 2008. "Revenue Management for a Primary-Care Clinic in the Presence of Patient Choice," Operations Research, INFORMS, vol. 56(3), pages 576-592, June.
    16. Lisa M. Maillart & Julie Simmons Ivy & Scott Ransom & Kathleen Diehl, 2008. "Assessing Dynamic Breast Cancer Screening Policies," Operations Research, INFORMS, vol. 56(6), pages 1411-1427, December.
    17. Jennifer E. Mason & Darin A. England & Brian T. Denton & Steven A. Smith & Murat Kurt & Nilay D. Shah, 2012. "Optimizing Statin Treatment Decisions for Diabetes Patients in the Presence of Uncertain Future Adherence," Medical Decision Making, , vol. 32(1), pages 154-166, January.
    18. Fatih Safa Erenay & Oguzhan Alagoz & Adnan Said, 2014. "Optimizing Colonoscopy Screening for Colorectal Cancer Prevention and Surveillance," Manufacturing & Service Operations Management, INFORMS, vol. 16(3), pages 381-400, July.
    19. McQuoid, Julia & Jowsey, Tanisha & Talaulikar, Girish, 2017. "Contextualising renal patient routines: Everyday space-time contexts, health service access, and wellbeing," Social Science & Medicine, Elsevier, vol. 183(C), pages 142-150.
    20. Oguzhan Alagoz & Lisa M. Maillart & Andrew J. Schaefer & Mark S. Roberts, 2004. "The Optimal Timing of Living-Donor Liver Transplantation," Management Science, INFORMS, vol. 50(10), pages 1420-1430, October.
    21. M. Reza Skandari & Steven M. Shechter & Nadia Zalunardo, 2015. "Optimal Vascular Access Choice for Patients on Hemodialysis," Manufacturing & Service Operations Management, INFORMS, vol. 17(4), pages 608-619, October.
    22. Chris P. Lee & Glenn M. Chertow & Stefanos A. Zenios, 2008. "Optimal Initiation and Management of Dialysis Therapy," Operations Research, INFORMS, vol. 56(6), pages 1428-1449, December.
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