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Lineage tracking reveals dynamic relationships of T cells in colorectal cancer
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- Pavlos Msaouel & Kai Yu & Ying Yuan & Jianfeng Chen & Xinmiao Yan & Menuka Karki & Fei Duan & Rahul A. Sheth & Priya Rao & Kanishka Sircar & Amishi Y. Shah & Amado J. Zurita & Giannicola Genovese & Mi, 2025. "Sitravatinib in combination with nivolumab plus ipilimumab in patients with advanced clear cell renal cell carcinoma: a phase 1 trial," Nature Communications, Nature, vol. 16(1), pages 1-18, December.
- Keyong Sun & Runda Xu & Fuhai Ma & Naixue Yang & Yang Li & Xiaofeng Sun & Peng Jin & Wenzhe Kang & Lemei Jia & Jianping Xiong & Haitao Hu & Yantao Tian & Xun Lan, 2022. "scRNA-seq of gastric tumor shows complex intercellular interaction with an alternative T cell exhaustion trajectory," Nature Communications, Nature, vol. 13(1), pages 1-19, December.
- Yanchuan Li & Huamei Li & Cheng Peng & Ge Meng & Yijun Lu & Honglin Liu & Li Cui & Huan Zhou & Zhu Xu & Lingyun Sun & Lihong Liu & Qing Xiong & Beicheng Sun & Shiping Jiao, 2024. "Unraveling the spatial organization and development of human thymocytes through integration of spatial transcriptomics and single-cell multi-omics profiling," Nature Communications, Nature, vol. 15(1), pages 1-25, December.
- Yang Liu & Shuang-Yan Ye & Shuai He & Dong-Mei Chi & Xiu-Zhi Wang & Yue-Feng Wen & Dong Ma & Run-Cong Nie & Pu Xiang & You Zhou & Zhao-Hui Ruan & Rou-Jun Peng & Chun-Ling Luo & Pan-Pan Wei & Guo-Wang , 2024. "Single-cell and spatial transcriptome analyses reveal tertiary lymphoid structures linked to tumour progression and immunotherapy response in nasopharyngeal carcinoma," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
- Victoria Stary & Ram V. Pandey & Julia List & Lisa Kleissl & Florian Deckert & Julijan Kabiljo & Johannes Laengle & Vasileios Gerakopoulos & Rudolf Oehler & Lukas Watzke & Matthias Farlik & Samuel W. , 2024. "Dysfunctional tumor-infiltrating Vδ1 + T lymphocytes in microsatellite-stable colorectal cancer," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Dongmei Chi & Kun Zhang & Jianxing Zhang & Zhaoli He & Hongxia Zhou & Wan Huang & Yang Liu & Jingxiu Huang & Weian Zeng & Xiaohui Bai & Chaopeng Ou & Handong Ouyang, 2025. "Astrocytic pleiotrophin deficiency in the prefrontal cortex contributes to stress-induced depressive-like responses in male mice," Nature Communications, Nature, vol. 16(1), pages 1-19, December.
- Samar Elorbany & Chiara Berlato & Larissa S. Carnevalli & Eleni Maniati & Simon T. Barry & Jun Wang & Ranjit Manchanda & Julia Kzhyshkowska & Frances Balkwill, 2024. "Immunotherapy that improves response to chemotherapy in high-grade serous ovarian cancer," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Tong Liu & Cheng Liu & Meisi Yan & Lei Zhang & Jing Zhang & Min Xiao & Zhigao Li & Xiaofan Wei & Hongquan Zhang, 2022. "Single cell profiling of primary and paired metastatic lymph node tumors in breast cancer patients," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Yan Li & Bing Wang & Wentao Yang & Fahan Ma & Jianling Zou & Kai Li & Subei Tan & Jinwen Feng & Yunzhi Wang & Zhaoyu Qin & Zhiyu Chen & Chen Ding, 2024. "Longitudinal plasma proteome profiling reveals the diversity of biomarkers for diagnosis and cetuximab therapy response of colorectal cancer," Nature Communications, Nature, vol. 15(1), pages 1-23, December.
- Tu-Xiong Huang & Hui-Si Huang & Shao-Wei Dong & Jia-Yan Chen & Bin Zhang & Hua-Hui Li & Tian-Tian Zhang & Qiang Xie & Qiao-Yun Long & Yang Yang & Lin-Yuan Huang & Pan Zhao & Jiong Bi & Xi-Feng Lu & Fa, 2024. "ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
- Silvia Tiberti & Carlotta Catozzi & Ottavio Croci & Mattia Ballerini & Danilo Cagnina & Chiara Soriani & Caterina Scirgolea & Zheng Gong & Jiatai He & Angeli D. Macandog & Amir Nabinejad & Carina B. N, 2022. "GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome," Nature Communications, Nature, vol. 13(1), pages 1-20, December.
- Yu-Fei Zhao & Zi-Ang Zuo & Zhe-Yun Li & Ye Yuan & Shi-Chai Hong & Wei-Guo Fu & Bin Zhou & Li-Xin Wang, 2024. "Integrated multi-omics profiling reveals neutrophil extracellular traps potentiate Aortic dissection progression," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Michele Bortolomeazzi & Lucia Montorsi & Damjan Temelkovski & Mohamed Reda Keddar & Amelia Acha-Sagredo & Michael J. Pitcher & Gianluca Basso & Luigi Laghi & Manuel Rodriguez-Justo & Jo Spencer & Fran, 2022. "A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially-resolved tissue phenotyping at single-cell resolution," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
- Sandra Tietscher & Johanna Wagner & Tobias Anzeneder & Claus Langwieder & Martin Rees & Bettina Sobottka & Natalie Souza & Bernd Bodenmiller, 2023. "A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
- Mei Lin & Xiao-Long Zhang & Rui You & You-Ping Liu & Hong-Min Cai & Li-Zhi Liu & Xue-Fei Liu & Xiong Zou & Yu-Long Xie & Ru-Hai Zou & Yi-Nuan Zhang & Rui Sun & Wei-Yi Feng & Hai-Yan Wang & Gui-Hua Tao, 2023. "Evolutionary route of nasopharyngeal carcinoma metastasis and its clinical significance," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
- Yiming Lu & Aiqing Yang & Cheng Quan & Yingwei Pan & Haoyun Zhang & Yuanfeng Li & Chengming Gao & Hao Lu & Xueting Wang & Pengbo Cao & Hongxia Chen & Shichun Lu & Gangqiao Zhou, 2022. "A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
- Xuan-Zhang Huang & Min-Jiao Pang & Jia-Yi Li & Han-Yu Chen & Jing-Xu Sun & Yong-Xi Song & Hong-Jie Ni & Shi-Yu Ye & Shi Bai & Teng-Hui Li & Xin-Yu Wang & Jing-Yuan Lu & Jin-Jia Yang & Xun Sun & Jason , 2023. "Single-cell sequencing of ascites fluid illustrates heterogeneity and therapy-induced evolution during gastric cancer peritoneal metastasis," Nature Communications, Nature, vol. 14(1), pages 1-22, December.
- Handong Sun & Lishen Zhang & Zhonglin Wang & Danling Gu & Mengyan Zhu & Yun Cai & Lu Li & Jiaqi Tang & Bin Huang & Bakwatanisa Bosco & Ning Li & Lingxiang Wu & Wei Wu & Liangyu Li & Yuan Liang & Lin L, 2023. "Single-cell transcriptome analysis indicates fatty acid metabolism-mediated metastasis and immunosuppression in male breast cancer," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
- Lilong Liu & Yaxin Hou & Changqi Deng & Zhen Tao & Zhaohui Chen & Junyi Hu & Ke Chen, 2022. "Single cell sequencing reveals that CD39 inhibition mediates changes to the tumor microenvironment," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
- Vidhya M. Ravi & Nicolas Neidert & Paulina Will & Kevin Joseph & Julian P. Maier & Jan Kückelhaus & Lea Vollmer & Jonathan M. Goeldner & Simon P. Behringer & Florian Scherer & Melanie Boerries & Marie, 2022. "T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
- Jingjing Qi & Hongxiang Sun & Yao Zhang & Zhengting Wang & Zhenzhen Xun & Ziyi Li & Xinyu Ding & Rujuan Bao & Liwen Hong & Wenqing Jia & Fei Fang & Hongzhi Liu & Lei Chen & Jie Zhong & Duowu Zou & Lia, 2022. "Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancer," Nature Communications, Nature, vol. 13(1), pages 1-20, December.
- Hussein A. Abbas & Dapeng Hao & Katarzyna Tomczak & Praveen Barrodia & Jin Seon Im & Patrick K. Reville & Zoe Alaniz & Wei Wang & Ruiping Wang & Feng Wang & Gheath Al-Atrash & Koichi Takahashi & Jing , 2021. "Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
- Sarah Cappuyns & Gino Philips & Vincent Vandecaveye & Bram Boeckx & Rogier Schepers & Thomas Van Brussel & Ingrid Arijs & Aurelie Mechels & Ayse Bassez & Francesca Lodi & Joris Jaekers & Halit Topal &, 2023. "PD-1- CD45RA+ effector-memory CD8 T cells and CXCL10+ macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
- Laura Yerly & Christine Pich-Bavastro & Jeremy Domizio & Tania Wyss & Stéphanie Tissot-Renaud & Michael Cangkrama & Michel Gilliet & Sabine Werner & François Kuonen, 2022. "Integrated multi-omics reveals cellular and molecular interactions governing the invasive niche of basal cell carcinoma," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
- Alexander H. Lee & Lu Sun & Aaron Y. Mochizuki & Jeremy G. Reynoso & Joey Orpilla & Frances Chow & Jenny C. Kienzler & Richard G. Everson & David A. Nathanson & Steven J. Bensinger & Linda M. Liau & T, 2021. "Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma," Nature Communications, Nature, vol. 12(1), pages 1-16, December.
- Cui-Lian Guo & Chong-Shu Wang & Zhi-Chao Wang & Fei-Fan Liu & Lin Liu & Yang Yang & Xia Li & Bei Guo & Ruo-Yu Lu & Bo Liao & Jin-Xin Liu & Hai Wang & Jia Song & Yin Yao & Li-Ping Zhu & Di Yu & Zheng L, 2024. "Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
- Ignacio Heras-Murillo & Diego Mañanes & Pablo Munné & Vanessa Núñez & Jessica Herrera & Mauro Catalá-Montoro & Maite Alvarez & Miguel A. del Pozo & Ignacio Melero & Stefanie K. Wculek & David Sancho, 2025. "Immunotherapy with conventional type-1 dendritic cells induces immune memory and limits tumor relapse," Nature Communications, Nature, vol. 16(1), pages 1-17, December.