Author
Listed:
- Vladimir M. Lakhtin
(G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology, Russia)
- Mikhail V. Lakhtin
(G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology, Russia)
- Valeriy Yu. Davydkin
(G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology, Russia)
- Alexandra V. Melikhova
(G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology, Russia)
- Igor Yu. Davydkin
(G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology, Russia)
- Olga G. Zhilenkova
(G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology, Russia)
Abstract
Examples of the nomenclature enzymes of all known classes with intrinsic lectin properties are represented, described and ordered. Such bi/multifunctional enzymes (enzybiotics) act as communicative agents, possess independent carbohydrate binding motifs, domains, epitopes or modules within subunit/molecule or supra-molecular assembly (free or solid-phased). Lectin part serve as modulator, switch and/or navigator of the whole resulting pattern enzyme (involving both catalytic center and lectinic sites) specificities toward targets. These enzybiotics (native and recombinant) as well as lectinbiotics (lectin-biotics) with intrinsic enzyme activities and high communicative potential possess promising broad prospects in food industry, medical biotechnology, prophylaxis and therapy. Among examples there are probiotic lectin enzybiotics (mainly from bifidobacteria and lactobacilli) that can serve perspective metabolite postbiotic systems for support or correction of the healthy individual or the patient mucosal open cavity biotope pathological status, respectively. Lectin-enzyme relationships improve platform for constructing advanced autoregulated systems influencing interactome at all levels of the organism. They support a lot of possible innovations in industrial biotechnology and medicine.
Suggested Citation
Handle:
RePEc:epw:ejbio0:v:2:y:2021:i:1:id:17150
DOI: 10.24018/ejbio.2021.2.1.150
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