Use of Cannabis in people with autism spectrum disorder

Introduction: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, social interaction, and repetitive or stereotyped behaviors in those affected. It presents with a wide range of symptoms, which can vary from mild to severe. Method: a search was conducted in the PubMed, SciELO databases, and the book Cannabis Medicinal. Articles were downloaded from the cited platforms to make the appropriate citations and references in Portuguese, Spanish, and English, covering the last 5 years. Results: The use of medicinal cannabis in treating Autism Spectrum Disorder (ASD) has shown potential in improving symptoms such as hyperactivity, aggression, self-harm, sleep disturbances, and anxiety. Recent studies highlight that cannabinoids, particularly cannabidiol (CBD), may be a safe and effective option for relieving these symptoms and improving patients' quality of life. However, it is essential to have more robust and long-term research to assess its safety and adverse effects. Despite promising results, the need for professional monitoring and individualized treatment is emphasized to optimize benefits and mitigate possible risks. Conclusions: this treatment is highly individualized and personalized, encompassing not only pharmacological interventions but also dietary adjustments, supplements, and social behavior strategies, with cannabis use being a supplementary alternative.