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Hepatitis B Incidence in Individuals with Chronic Kidney Disorder: A Meta-Analysis

Author

Listed:
  • Kumar Kumawat
  • Kumar Bansal
  • Lovely
  • Goyal
  • Srinath
  • Vashisht

Abstract

The hepatitis B virus is a major contributor to liver disease and has many non-liver symptoms. In addition to the significant impairment and mortality that HBV causes in the population, the most recent study indicates the role that HBV plays in the initiation and development of Chronic Kidney Disease (CKD). The causal relationship between HBV and CKD has yet to be fully elucidated. Antiviral nucleos (t) medicine compounds for HBV are already available, and they are very effective for individuals with chronic kidney disease. An increased probability of CKD has been identified in those with HBV, according to a recent meta-analysis of clinical data. Based on the most recent review, we identified six separate clinical trials. There was too much variation to draw any firm conclusions. Several proposed reasons account for the increased risk of CKD in HBsAg optimistic patients. Additional data links treatment with nucleos(t)ide equivalents to a decreased risk of end-stage renal disease (ESRD) and links undiagnosed HBV to an increased risk of ESRD in the CKD population. They advise that kidney activity and urine alterations be measured at the outset and periodically in HBV participants.

Suggested Citation

Handle: RePEc:dbk:health:v:4:y:2025:i::p:619:id:619
DOI: 10.56294/hl2025619
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