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A retrospective analysis of glucose intolerance in individuals with liver cirrhosis

Author

Listed:
  • J
  • Sriram
  • Thabassum Z
  • Sudhir
  • Parmar
  • Agarwal

Abstract

The prediction of liver cirrhosis can be affected by diabetes mellitus (DM), a worldwide health issue that can impair the body's metabolic processes. Patients with liver cirrhosis benefit from knowing their glycemic status that problems can be anticipated and treated sooner, improving their prognosis. Impaired glucose tolerance (IGT) can be understated utilizing standard approaches. The research utilized an oral glucose tolerance test (OGTT) to recognize the popularity of IGT in individuals with liver cirrhosis who are not diagnosed with diabetes. The dataset for the research would include individuals diagnosed with liver cirrhosis who have not been diagnosed with diabetes mellitus. It would encompass demographic details (N=80) such as age, gender, and medical history, along with liver function parameters including liver enzymes, bilirubin, and albumin levels. Statistical analysis was conducted using IBM SPSS Statistics (Version 26.0) software. Independent t-tests were applied to compare continuous variables, while chi-square tests were used to analyze categorical variables. The frequency of IGT in the research was 36.47 percent. In addition to IGT, observed that DM was more frequent in those aged 31-40; of the 80 patients analyzed in research, 24.71 percent were diagnosed with DM. OGTT can improve liver cirrhosis prognosis by detecting diabetes and insulin resistance in patients, potentially reducing the risk of complications due to poor glucose management.

Suggested Citation

Handle: RePEc:dbk:health:v:4:y:2025:i::p:616:id:616
DOI: 10.56294/hl2025616
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