Impact of Hydrogen Peroxide Tooth Whitening on Candida albicans Colonization

Introduction: *Candida albicans* is a fungus that is part of the oral microflora in 30-50% of the population. Its ability to alternate between different morphological forms, such as yeasts, pseudohyphae and hyphae, gives it a remarkable biological plasticity. This study evaluated the impact of tooth whitening with 35% hydrogen peroxide on the adherence of *C. albicans* to tooth enamel, exploring the factors that influence its colonization and virulence. Development: It was observed that *C. albicans* uses specific adhesins and components of its cell wall to adhere to surfaces such as dental enamel. This process, together with the formation of biofilms, increases its resistance to treatment and protection against the immune system. The action of hydrogen peroxide, although effective as an oxidizing agent, can modify the enamel surface, favoring the adherence of *C. albicans* and the interaction with bacteria such as *Streptococcus mutans*. These interactions enhance the formation of mixed biofilms, which represents a significant risk to oral health. Conclusions: The study concluded that tooth whitening with hydrogen peroxide can facilitate colonization of *C. albicans* due to changes in tooth enamel composition. Furthermore, it reaffirmed the importance of this fungus as an opportunistic pathogen and highlighted the need to implement preventive strategies in esthetic dental treatments. These strategies include the use of remineralizing agents and the strengthening of hygiene protocols to minimize associated risks. Future research will be key to better understand these interactions and develop more effective therapeutic approaches.