Grilichesian Breakthroughs: Inventions of Methods of Inventing and Firm Entry in Nanotechnology
AbstractMetamorphic progress (productivity growth much faster than average) is often driven by Grilichesian inventions of methods of inventing. For hybrid seed corn, the enabling invention was double-cross hybridization yielding highly productive seed corn that was not self-propagating. Biotechnology stemmed from recombinant DNA. Scanning probe microscopy is a key enabling discovery for nanotechnology. Nanotech publishing and patenting has grown phenomenally. Over half of nanotech authors are in the U.S. and 58 percent of those are in ten metropolitan areas. Like biotechnology, we find that firms enter nanotechnology where and when scientists are publishing breakthrough academic articles. A high average education level is also important, but the past level of venture-capital activity in a region is not. Breakthroughs in nanoscale science and engineering appear frequently to be transferred to industrial application with the active participation of discovering academic scientists. The need for top scientists' involvement provided important appropriability for biotechnology inventions, and a similar process appears to have started in nanotechnology.
Download InfoIf you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
Bibliographic InfoPaper provided by National Bureau of Economic Research, Inc in its series NBER Working Papers with number 9825.
Date of creation: Jul 2003
Date of revision:
Publication status: published as Michael DARBY & Lynne G. ZUCKER, 2005. "Grilichesian Breakthroughs: Inventions of Methods of Inventing and Firm Entry in Nanotechnology," Annales d'Economie et de Statistique, ENSAE, issue 79-80, pages 143-164.
Contact details of provider:
Postal: National Bureau of Economic Research, 1050 Massachusetts Avenue Cambridge, MA 02138, U.S.A.
Web page: http://www.nber.org
More information through EDIRC
Other versions of this item:
- Michael DARBY & Lynne G. ZUCKER, 2005. "Grilichesian Breakthroughs: Inventions of Methods of Inventing and Firm Entry in Nanotechnology," Annales d'Economie et de Statistique, ENSAE, issue 79-80, pages 143-164.
- Michael L. Darby & Lynne G. Zucker, 2010. "Grilichesian Breakthroughs: Inventions of Methods of Inventing and Firm Entry in Nanotechnology," NBER Chapters, in: Contributions in Memory of Zvi Griliches, pages 143-164 National Bureau of Economic Research, Inc.
- O31 - Economic Development, Technological Change, and Growth - - Technological Change; Research and Development; Intellectual Property Rights - - - Innovation and Invention: Processes and Incentives
- L63 - Industrial Organization - - Industry Studies: Manufacturing - - - Microelectronics; Computers; Communications Equipment
This paper has been announced in the following NEP Reports:
- NEP-ALL-2004-08-31 (All new papers)
- NEP-ENT-2004-08-31 (Entrepreneurship)
- NEP-INO-2004-08-31 (Innovation)
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Richard Jensen & Marie Thursby, 1998. "Proofs and Prototypes for Sale: The Tale of University Licensing," NBER Working Papers 6698, National Bureau of Economic Research, Inc.
This item has more than 25 citations. To prevent cluttering this page, these citations are listed on a separate page. reading list or among the top items on IDEAS.Access and download statisticsgeneral information about how to correct material in RePEc.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: ().
If references are entirely missing, you can add them using this form.