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A Review of the Psychometric Properties of Generic Utility Measures in Multiple Sclerosis

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  • Ayse Kuspinar
  • Nancy Mayo

Abstract

To our knowledge this is the first study to review the validity and reliability of generic utility measures in MS. The HUI3 demonstrated the strongest psychometric properties when compared with other utility measures. However, the HUI3 only measures impairment and excludes important components of HRQL such as participation restrictions. The EQ-5D, the SF-6D and the QWB scale, on the other hand, do include items on participation. However, these measures demonstrated a lack of content validity in MS by missing certain domains that were important to the disease, as well as difficulty in differentiating between different levels of disability. The addition of MS-specific ‘bolt-ons’ to generic utility measures and the development of an MS specific utility measure are possible areas of exploration for future research. Copyright Springer International Publishing Switzerland 2014

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  • Ayse Kuspinar & Nancy Mayo, 2014. "A Review of the Psychometric Properties of Generic Utility Measures in Multiple Sclerosis," PharmacoEconomics, Springer, vol. 32(8), pages 759-773, August.
    • Handle: RePEc:spr:pharme:v:32:y:2014:i:8:p:759-773
    DOI: 10.1007/s40273-014-0167-5
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    References listed on IDEAS

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    1. Brazier, John & Roberts, Jennifer & Deverill, Mark, 2002. "The estimation of a preference-based measure of health from the SF-36," Journal of Health Economics, Elsevier, vol. 21(2), pages 271-292, March.
    2. Jeff Richardson & Neil Atherton Day & Stuart Peacock & Angelo Iezzi, 2004. "Measurement of the Quality of Life for Economic Evaluation and the Assessment of Quality of Life (AQoL) Mark 2 Instrument," Australian Economic Review, The University of Melbourne, Melbourne Institute of Applied Economic and Social Research, vol. 37(1), pages 62-88, March.
    3. John Brazier & Jennifer Roberts & Aki Tsuchiya & Jan Busschbach, 2004. "A comparison of the EQ‐5D and SF‐6D across seven patient groups," Health Economics, John Wiley & Sons, Ltd., vol. 13(9), pages 873-884, September.
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    1. Aureliano Paolo Finch & John Edward Brazier & Clara Mukuria, 2018. "What is the evidence for the performance of generic preference-based measures? A systematic overview of reviews," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 19(4), pages 557-570, May.
    2. Suzi Claflin & Julie A. Campbell & Richard Norman & Deborah F. Mason & Tomas Kalincik & Steve Simpson-Yap & Helmut Butzkueven & William M. Carroll & Andrew J. Palmer & C. Leigh Blizzard & Ingrid van d, 2023. "Using the EQ-5D-5L to investigate quality-of-life impacts of disease-modifying therapy policies for people with multiple sclerosis (MS) in New Zealand," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 24(6), pages 939-950, August.

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