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Network vs. Pairwise Meta-Analyses: A Case Study of the Impact of an Evidence-Synthesis Paradigm on Value of Information Outcomes

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  • Zafar Zafari
  • Kristian Thorlund
  • J. FitzGerald
  • Carlo Marra
  • Mohsen Sadatsafavi

Abstract

Our case study shows that the choice of PMA or NMA can have significant effects on the EVI results. Under comparable conditions, the incorporation of more evidence in the NMA most likely increases the precision of estimates and therefore is likely to result in lower EVI outcomes. As our study demonstrates, the difference in EVI outcomes can be substantial, potentially affecting the decision to conduct research and the design of future research. Copyright Springer International Publishing Switzerland 2014

Suggested Citation

  • Zafar Zafari & Kristian Thorlund & J. FitzGerald & Carlo Marra & Mohsen Sadatsafavi, 2014. "Network vs. Pairwise Meta-Analyses: A Case Study of the Impact of an Evidence-Synthesis Paradigm on Value of Information Outcomes," PharmacoEconomics, Springer, vol. 32(10), pages 995-1004, October.
    • Handle: RePEc:spr:pharme:v:32:y:2014:i:10:p:995-1004
    DOI: 10.1007/s40273-014-0179-1
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    References listed on IDEAS

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    4. Drummond, Michael F. & Sculpher, Mark J. & Torrance, George W. & O'Brien, Bernie J. & Stoddart, Greg L., 2005. "Methods for the Economic Evaluation of Health Care Programmes," OUP Catalogue, Oxford University Press, edition 3, number 9780198529453.
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    Cited by:

    1. Farah Wasim Aribi Al-Zoobaee & Loo Yee Shen & Sajesh K. Veettil & Divya Gopinath & Mari Kannan Maharajan & Rohit Kunnath Menon, 2020. "Antiviral Agents for the Prevention and Treatment of Herpes Simplex Virus Type-1 Infection in Clinical Oncology: A Network Meta-Analysis," IJERPH, MDPI, vol. 17(23), pages 1-25, November.

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