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An Assessment and Extension of the Mechanism-Based Approach to the Identification of Age-Period-Cohort Models

Author

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  • Maarten J. Bijlsma

    (University of Groningen
    Max Planck Institute for Demographic Research)

  • Rhian M. Daniel

    (London School of Hygiene and Tropical Medicine)

  • Fanny Janssen

    (University of Groningen
    University of Groningen)

  • Bianca L. De Stavola

    (London School of Hygiene and Tropical Medicine)

Abstract

Many methods have been proposed to solve the age-period-cohort (APC) linear identification problem, but most are not theoretically informed and may lead to biased estimators of APC effects. One exception is the mechanism-based approach recently proposed and based on Pearl’s front-door criterion; this approach ensures consistent APC effect estimators in the presence of a complete set of intermediate variables between one of age, period, cohort, and the outcome of interest, as long as the assumed parametric models for all the relevant causal pathways are correct. Through a simulation study mimicking APC data on cardiovascular mortality, we demonstrate possible pitfalls that users of the mechanism-based approach may encounter under realistic conditions: namely, when (1) the set of available intermediate variables is incomplete, (2) intermediate variables are affected by two or more of the APC variables (while this feature is not acknowledged in the analysis), and (3) unaccounted confounding is present between intermediate variables and the outcome. Furthermore, we show how the mechanism-based approach can be extended beyond the originally proposed linear and probit regression models to incorporate all generalized linear models, as well as nonlinearities in the predictors, using Monte Carlo simulation. Based on the observed biases resulting from departures from underlying assumptions, we formulate guidelines for the application of the mechanism-based approach (extended or not).

Suggested Citation

  • Maarten J. Bijlsma & Rhian M. Daniel & Fanny Janssen & Bianca L. De Stavola, 2017. "An Assessment and Extension of the Mechanism-Based Approach to the Identification of Age-Period-Cohort Models," Demography, Springer;Population Association of America (PAA), vol. 54(2), pages 721-743, April.
    • Handle: RePEc:spr:demogr:v:54:y:2017:i:2:d:10.1007_s13524-017-0562-6
    DOI: 10.1007/s13524-017-0562-6
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    References listed on IDEAS

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    1. Andrew Bell & Kelvyn Jones, 2014. "Another 'futile quest'? A simulation study of Yang and Land's Hierarchical Age-Period-Cohort model," Demographic Research, Max Planck Institute for Demographic Research, Rostock, Germany, vol. 30(11), pages 333-360.
    2. Liying Luo, 2013. "Assessing Validity and Application Scope of the Intrinsic Estimator Approach to the Age-Period-Cohort Problem," Demography, Springer;Population Association of America (PAA), vol. 50(6), pages 1945-1967, December.
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    Cited by:

    1. Gary Venter, 2018. "Regularized Age-Period-Cohort Modeling of Opioid Mortality Rates," Applied Economics and Finance, Redfame publishing, vol. 5(4), pages 12-23, July.

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