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Economic Evaluation of Vaccination Programs: The Impact of Herd-Immunity

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  • M. Brisson
  • W. J. Edmunds

Abstract

The unique characteristic of vaccination is that it not only reduces the incidence of disease in those immunized but also indirectly protects nonvaccinated susceptibles against infection (produces herd-immunity). The bulk of economic evaluations of vaccination programs continue to use models that cannot take into account the indirect effects produced by herd-immunity. Here, the authors illustrate the importance of incorporating herd-immunity externalities when assessing the cost-effectiveness of vaccination programs. To do this, they compare 2 methods of estimating the benefits of routine mass vaccination: one that includes herd-immunity (dynamic approach) and one that does not (static approach). Finally, they use the results to clarify a number of misconceptions that are common in the literature concerning herd immunity and dynamical effects produced by models.

Suggested Citation

  • M. Brisson & W. J. Edmunds, 2003. "Economic Evaluation of Vaccination Programs: The Impact of Herd-Immunity," Medical Decision Making, , vol. 23(1), pages 76-82, January.
    • Handle: RePEc:sae:medema:v:23:y:2003:i:1:p:76-82
    DOI: 10.1177/0272989X02239651
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    Citations

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    Cited by:

    1. Laurent Coudeville & Annelies Van Rie & Denis Getsios & J Jaime Caro & Pascal Crépey & Van Hung Nguyen, 2009. "Adult Vaccination Strategies for the Control of Pertussis in the United States: An Economic Evaluation Including the Dynamic Population Effects," PLOS ONE, Public Library of Science, vol. 4(7), pages 1-9, July.
    2. Anna K. Lugnér & Sido D. Mylius & Jacco Wallinga, 2010. "Dynamic versus static models in cost‐effectiveness analyses of anti‐viral drug therapy to mitigate an influenza pandemic," Health Economics, John Wiley & Sons, Ltd., vol. 19(5), pages 518-531, May.
    3. Iwamura, Yoshiro & Tanimoto, Jun, 2018. "Realistic decision-making processes in a vaccination game," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 494(C), pages 236-241.
    4. Wang, Qingqing & Du, Chunpeng & Geng, Yini & Shi, Lei, 2020. "Historical payoff can not overcome the vaccination dilemma on Barabási–Albert scale-free networks," Chaos, Solitons & Fractals, Elsevier, vol. 130(C).
    5. Greg Plosker, 2011. "Rotavirus Vaccine RIX4414 (Rotarix™)," PharmacoEconomics, Springer, vol. 29(11), pages 989-1009, November.
    6. Rachel Elliott & Helen Weatherly & Neil Hawkins & Gillian Cranny & Duncan Chambers & Lindsey Myers & Alison Eastwood & Mark Sculpher, 2010. "An economic model for the prevention of MRSA infections after surgery: non-glycopeptide or glycopeptide antibiotic prophylaxis?," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 11(1), pages 57-66, February.
    7. Sun-Young Kim & Sue Goldie, 2008. "Cost-Effectiveness Analyses of Vaccination Programmes," PharmacoEconomics, Springer, vol. 26(3), pages 191-215, March.
    8. Mario Songane, 2018. "Challenges for nationwide vaccine delivery in African countries," International Journal of Health Economics and Management, Springer, vol. 18(2), pages 197-219, June.
    9. Caroline L. Trotter & W. John Edmunds, 2006. "Reassessing the Cost-Effectiveness of Meningococcal Serogroup C Conjugate (MCC) Vaccines Using a Transmission Dynamic Model," Medical Decision Making, , vol. 26(1), pages 38-47, January.
    10. Wang, Jianwei & Xu, Wenshu & Chen, Wei & Yu, Fengyuan & He, Jialu, 2021. "Information sharing can suppress the spread of epidemics: Voluntary vaccination game on two-layer networks," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 583(C).
    11. Sang-Man Kim & Arben Asllani, 2013. "Using simulation to establish appropriate vaccination rates and copayment policies from a cost perspective," Service Business, Springer;Pan-Pacific Business Association, vol. 7(3), pages 437-457, September.
    12. Benyun Shi & Guangliang Liu & Hongjun Qiu & Yu-Wang Chen & Shaoliang Peng, 2019. "Voluntary Vaccination through Perceiving Epidemic Severity in Social Networks," Complexity, Hindawi, vol. 2019, pages 1-13, February.
    13. Choudhury, Agnitra Roy & Polachek, Solomon, 2019. "The Impact of Paid Family Leave on the Timing of Infant Vaccinations," IZA Discussion Papers 12483, Institute of Labor Economics (IZA).
    14. Arnold Kamis & Yuji Zhang & Tamara Kamis, 2017. "A Multiyear Model of Influenza Vaccination in the United States," IJERPH, MDPI, vol. 14(8), pages 1-14, July.
    15. Andrea Anonychuk & Andrea Tricco & Chris Bauch & Ba’ Pham & Vladimir Gilca & Bernard Duval & Ava John-Baptiste & Gloria Woo & Murray Krahn, 2008. "Cost-Effectiveness Analyses of Hepatitis A Vaccine," PharmacoEconomics, Springer, vol. 26(1), pages 17-32, January.
    16. Radboud J. Duintjer Tebbens & Kimberly M. Thompson, 2009. "Priority Shifting and the Dynamics of Managing Eradicable Infectious Diseases," Management Science, INFORMS, vol. 55(4), pages 650-663, April.

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