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COVID-19 vaccines and mental distress

Author

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  • Francisco Perez-Arce
  • Marco Angrisani
  • Daniel Bennett
  • Jill Darling
  • Arie Kapteyn
  • Kyla Thomas

Abstract

Background: The COVID-19 pandemic brought about large increases in mental distress. The uptake of COVID-19 vaccines is expected to significantly reduce health risks, improve economic and social outcomes, with potential benefits to mental health. Purpose: To examine short-term changes in mental distress following the receipt of the first dose of the COVID-19 vaccine. Methods: Participants included 8,003 adults from the address-based sampled, nationally representative Understanding America Study (UAS), surveyed at regular intervals between March 10, 2020, and March 31, 2021 who completed at least two waves of the survey. Respondents answered questions about COVID-19 vaccine status and self-reported mental distress as measured with the four-item Patient Health Questionnaire (PHQ-4). Fixed-effects regression models were used to identify the change in PHQ-4 scores and categorical indicators of mental distress resulting from the application of the first dose of the COVID-19 vaccine. Results: People who were vaccinated between December 2020 and March 2021 reported decreased mental distress levels in the surveys conducted after receiving the first dose. The fixed-effects estimates show an average effect of receiving the vaccine equivalent to 4% of the standard deviation of PHQ-4 scores (p-value

Suggested Citation

  • Francisco Perez-Arce & Marco Angrisani & Daniel Bennett & Jill Darling & Arie Kapteyn & Kyla Thomas, 2021. "COVID-19 vaccines and mental distress," PLOS ONE, Public Library of Science, vol. 16(9), pages 1-11, September.
    • Handle: RePEc:plo:pone00:0256406
    DOI: 10.1371/journal.pone.0256406
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    References listed on IDEAS

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    1. Fabrice Kämpfen & Iliana V Kohler & Alberto Ciancio & Wändi Bruine de Bruin & Jürgen Maurer & Hans-Peter Kohler, 2020. "Predictors of mental health during the Covid-19 pandemic in the US: Role of economic concerns, health worries and social distancing," PLOS ONE, Public Library of Science, vol. 15(11), pages 1-13, November.
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    Cited by:

    1. Quintana-Domeque, Climent & Zeng, Jingya, 2023. "COVID-19 and Mental Health: Natural Experiments of the Costs of Lockdowns," IZA Discussion Papers 16532, Institute of Labor Economics (IZA).
    2. Virat Agrawal & Jonathan H. Cantor & Neeraj Sood & Christopher M. Whaley, 2021. "The Impact of the COVID-19 Vaccine Distribution on Mental Health Outcomes," NBER Working Papers 29593, National Bureau of Economic Research, Inc.
    3. Akay, Alpaslan, 2022. "The local and global mental health effects of the Covid-19 pandemic," Economics & Human Biology, Elsevier, vol. 45(C).
    4. Durmuş Burak, 2023. "The Effect of Risk and Protective Factors on Primary School Students’ COVID-19 Anxiety: Back to School After the Pandemic," Child Indicators Research, Springer;The International Society of Child Indicators (ISCI), vol. 16(1), pages 29-51, February.
    5. Burak, Durmus, 2023. "Psychometric properties of pandemic awareness scale for students aged 8–12: The case of COVID-19," Children and Youth Services Review, Elsevier, vol. 149(C).

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