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Longitudinal associations between racial discrimination and hippocampal and white matter hyperintensity volumes among older Black adults

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  • Zahodne, Laura B.
  • Sharifian, Neika
  • Kraal, A. Zarina
  • Morris, Emily P.
  • Sol, Ketlyne
  • Zaheed, Afsara B.
  • Meister, Lindsey
  • Mayeux, Richard
  • Schupf, Nicole
  • Manly, Jennifer J.
  • Brickman, Adam M.

Abstract

Non-Hispanic Black older adults are at higher risk of Alzheimer's disease and related dementias (ADRD) than non-Hispanic Whites, which reflects racial disparities in both brain and cognitive health. Discrimination may contribute to these disparities, but much of the research on discrimination and ADRD outcomes is cross-sectional and/or does not disaggregate experiences of discrimination by attribution. Focusing specifically on racial discrimination and considering longitudinal brain outcomes may advance our understanding of the role of discrimination in explaining disproportionate rates of ADRD among non-Hispanic Black older adults.

Suggested Citation

  • Zahodne, Laura B. & Sharifian, Neika & Kraal, A. Zarina & Morris, Emily P. & Sol, Ketlyne & Zaheed, Afsara B. & Meister, Lindsey & Mayeux, Richard & Schupf, Nicole & Manly, Jennifer J. & Brickman, Ada, 2023. "Longitudinal associations between racial discrimination and hippocampal and white matter hyperintensity volumes among older Black adults," Social Science & Medicine, Elsevier, vol. 316(C).
  • Handle: RePEc:eee:socmed:v:316:y:2023:i:c:s0277953622000958
    DOI: 10.1016/j.socscimed.2022.114789
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    References listed on IDEAS

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    1. Laura B ZahodnePhD & Ketlyne SolPhD & Zarina KraalMS, 2019. "Psychosocial Pathways to Racial/Ethnic Inequalities in Late-Life Memory Trajectories," The Journals of Gerontology: Series B, The Gerontological Society of America, vol. 74(3), pages 409-418.
    2. Williams, David R. & Gonzalez, Hector M. & Williams, Stacey & Mohammed, Selina A. & Moomal, Hashim & Stein, Dan J., 2008. "Perceived discrimination, race and health in South Africa," Social Science & Medicine, Elsevier, vol. 67(3), pages 441-452, August.
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