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Bayesian Dose-Finding in Phase I/II Clinical Trials Using Toxicity and Efficacy Odds Ratios

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  • Guosheng Yin
  • Yisheng Li
  • Yuan Ji

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  • Guosheng Yin & Yisheng Li & Yuan Ji, 2006. "Bayesian Dose-Finding in Phase I/II Clinical Trials Using Toxicity and Efficacy Odds Ratios," Biometrics, The International Biometric Society, vol. 62(3), pages 777-787, September.
    • Handle: RePEc:bla:biomet:v:62:y:2006:i:3:p:777-787
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    File URL: http://hdl.handle.net/10.1111/j.1541-0420.2006.00534.x
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    References listed on IDEAS

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    1. B. Nebiyou Bekele & Yu Shen, 2005. "A Bayesian Approach to Jointly Modeling Toxicity and Biomarker Expression in a Phase I/II Dose-Finding Trial," Biometrics, The International Biometric Society, vol. 61(2), pages 343-354, June.
    2. Peter F. Thall & John D. Cook, 2004. "Dose-Finding Based on Efficacy–Toxicity Trade-Offs," Biometrics, The International Biometric Society, vol. 60(3), pages 684-693, September.
    3. Mauro Gasparini & Jeffrey Eisele, 2000. "A Curve-Free Method for Phase I Clinical Trials," Biometrics, The International Biometric Society, vol. 56(2), pages 609-615, June.
    4. Saurabh Mukhopadhyay, 2000. "Bayesian Nonparametric Inference on the Dose Level with Specified Response Rate," Biometrics, The International Biometric Society, vol. 56(1), pages 220-226, March.
    5. Peter F. Thall & Su-Chun Chengt, 1999. "Treatment Comparisons Based on Two-Dimensional Safety and Efficacy Alternatives in Oncology Trials," Biometrics, The International Biometric Society, vol. 55(3), pages 746-753, September.
    6. Ying Kuen Cheung, 2002. "On the Use of Nonparametric Curves in Phase I Trials with Low Toxicity Tolerance," Biometrics, The International Biometric Society, vol. 58(1), pages 237-240, March.
    7. Anastasia Ivanova, 2003. "A New Dose-Finding Design for Bivariate Outcomes," Biometrics, The International Biometric Society, vol. 59(4), pages 1001-1007, December.
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    Cited by:

    1. Drovandi, Christopher C. & McGree, James M. & Pettitt, Anthony N., 2013. "Sequential Monte Carlo for Bayesian sequentially designed experiments for discrete data," Computational Statistics & Data Analysis, Elsevier, vol. 57(1), pages 320-335.
    2. Haitao Pan & Ping Huang & Zuoren Wang & Ling Wang & Chanjuan Li & Jielai Xia, 2013. "A Novel Bayesian Seamless Phase I/II Design," PLOS ONE, Public Library of Science, vol. 8(9), pages 1-6, September.
    3. Peter Müller & Don A. Berry & Andrew P. Grieve & Michael Krams, 2006. "A Bayesian Decision-Theoretic Dose-Finding Trial," Decision Analysis, INFORMS, vol. 3(4), pages 197-207, December.
    4. Yuxi Tao & Junlin Liu & Zhihui Li & Jinguan Lin & Tao Lu & Fangrong Yan, 2013. "Dose-Finding Based on Bivariate Efficacy-Toxicity Outcome Using Archimedean Copula," PLOS ONE, Public Library of Science, vol. 8(11), pages 1-6, November.
    5. Ying Yuan & Guosheng Yin, 2009. "Bayesian dose finding by jointly modelling toxicity and efficacy as time‐to‐event outcomes," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 58(5), pages 719-736, December.
    6. José L. Jiménez & Mourad Tighiouart, 2022. "Combining cytotoxic agents with continuous dose levels in seamless phase I‐II clinical trials," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 71(5), pages 1996-2013, November.
    7. Peter F. Thall & Hoang Q. Nguyen & Ralph G. Zinner, 2017. "Parametric dose standardization for optimizing two-agent combinations in a phase I–II trial with ordinal outcomes," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 66(1), pages 201-224, January.
    8. Ying Kuen Cheung, 2014. "Simple benchmark for complex dose finding studies," Biometrics, The International Biometric Society, vol. 70(2), pages 389-397, June.

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