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A Bayesian dose finding design for oncology clinical trials of combinational biological agents

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  • Chunyan Cai
  • Ying Yuan
  • Yuan Ji

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  • Chunyan Cai & Ying Yuan & Yuan Ji, 2014. "A Bayesian dose finding design for oncology clinical trials of combinational biological agents," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 63(1), pages 159-173, January.
    • Handle: RePEc:bla:jorssc:v:63:y:2014:i:1:p:159-173
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    File URL: http://hdl.handle.net/10.1111/rssc.12039
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    References listed on IDEAS

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    1. Nolan A. Wages & Mark R. Conaway & John O'Quigley, 2011. "Continual Reassessment Method for Partial Ordering," Biometrics, The International Biometric Society, vol. 67(4), pages 1555-1563, December.
    2. Xuelin Huang & Swati Biswas & Yasuhiro Oki & Jean-Pierre Issa & Donald A. Berry, 2007. "A Parallel Phase I/II Clinical Trial Design for Combination Therapies," Biometrics, The International Biometric Society, vol. 63(2), pages 429-436, June.
    3. Peter F. Thall & John D. Cook, 2004. "Dose-Finding Based on Efficacy–Toxicity Trade-Offs," Biometrics, The International Biometric Society, vol. 60(3), pages 684-693, September.
    4. Guosheng Yin & Ying Yuan, 2009. "Bayesian dose finding in oncology for drug combinations by copula regression," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 58(2), pages 211-224, May.
    5. Kai Wang & Anastasia Ivanova, 2005. "Two-Dimensional Dose Finding in Discrete Dose Space," Biometrics, The International Biometric Society, vol. 61(1), pages 217-222, March.
    6. Yuan, Ying & Yin, Guosheng, 2011. "Robust EM Continual Reassessment Method in Oncology Dose Finding," Journal of the American Statistical Association, American Statistical Association, vol. 106(495), pages 818-831.
    7. Peter F. Thall & Randall E. Millikan & Peter Mueller & Sang-Joon Lee, 2003. "Dose-Finding with Two Agents in Phase I Oncology Trials," Biometrics, The International Biometric Society, vol. 59(3), pages 487-496, September.
    8. Mark R. Conaway & Stephanie Dunbar & Shyamal D. Peddada, 2004. "Designs for Single- or Multiple-Agent Phase I Trials," Biometrics, The International Biometric Society, vol. 60(3), pages 661-669, September.
    9. Thomas M. Braun & Shufang Wang, 2010. "A Hierarchical Bayesian Design for Phase I Trials of Novel Combinations of Cancer Therapeutic Agents," Biometrics, The International Biometric Society, vol. 66(3), pages 805-812, September.
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    Cited by:

    1. Beibei Guo & Elizabeth Garrett‐Mayer & Suyu Liu, 2021. "A Bayesian phase I/II design for cancer clinical trials combining an immunotherapeutic agent with a chemotherapeutic agent," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 70(5), pages 1210-1229, November.
    2. Nolan A. Wages & Craig L. Slingluff, 2020. "Flexible Phase I–II Design for Partially Ordered Regimens with Application to Therapeutic Cancer Vaccines," Statistics in Biosciences, Springer;International Chinese Statistical Association, vol. 12(2), pages 104-123, July.
    3. José L. Jiménez & Mourad Tighiouart, 2022. "Combining cytotoxic agents with continuous dose levels in seamless phase I‐II clinical trials," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 71(5), pages 1996-2013, November.
    4. Patricia Gilholm & Kerrie Mengersen & Helen Thompson, 2020. "Identifying latent subgroups of children with developmental delay using Bayesian sequential updating and Dirichlet process mixture modelling," PLOS ONE, Public Library of Science, vol. 15(6), pages 1-17, June.

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